Akriderm Genta, cream, 30g

Composition

1 gram of cream contains

0.64 mg of betamethasone dipropionate (equivalent to 0.5 mg of betamethasone);

gentamicin sulfate-1 mg

Pharmacological action

Akriderm GENTA is a combined drug for external use that has anti-inflammatory, anti-allergic and antibacterial effects.

Betamethasone dipropionate is a glucocorticosteroid that has anti-inflammatory, anti-allergic, anti-exudative, anti-edematous and antipruritic effects. It inhibits the accumulation of white blood cells, the release of lysosomal enzymes and pro-inflammatory mediators in the inflammatory focus, inhibits phagocytosis, reduces vascular-tissue permeability, and prevents the formation of inflammatory edema.

Gentamicin is a broad-spectrum antibiotic from the group of aminoglycosides. It has a bactericidal effect against pathogens of primary and secondary bacterial skin infections. Active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae; gram-positive bacteria: Streptococcus spp. (sensitive strains of beta-and alpha-hemolytic streptococcus group A), Staphytococcus spp. (coagulase-positive, coagulase-negative, and some penicillinase-producing strains). Inactive against anaerobes, fungi and viruses.

Indications

Treatment of steroid-sensitive dermatoses complicated by primary and / or secondary bacterial infection, eczema (atopic, pediatric, monetoid), limited and diffuse allergodermatoses, including those complicated by gentamicin-sensitive infection, dermatitis (simple and allergic), atopic dermatitis, solar dermatitis, exfoliative and radiation dermatitis, diaper rash, psoriasis, pruritus.

Use during pregnancy and lactation

This is possible if the expected effect of therapy on the mother exceeds the potential risk to the fetus. Contraindicated during pregnancy in large doses and for a long time. Breast-feeding should be discontinued for the duration of treatment.

Contraindications

Hypersensitivity to the components of the drug. Skin tuberculosis, viral skin infections, vaccinations, perioral dermatitis, rosacea.

Side effects

Burning, dry skin, folliculitis, hypertrichosis, hypopigmentation allergic contact dermatitis, skin atrophy, striae, sweating.

How to take, course of use and dosage

Akriderm GHENT is applied in a thin layer on the inflamed surface twice a day, lightly rubbing. In milder cases, a single use is sufficient. The duration of treatment is determined individually and depends on the nosological form and severity of the disease and is usually 1-2 (rarely 4 weeks). If a long course of therapy is necessary, it is recommended to use the drug less often, for example, every other day.

When treating chronic diseases under the constant supervision of a doctor, treatment should be continued for some time after all symptoms disappear, in order to avoid relapse of the disease. The use of the drug in children under 12 years of age is carried out under the supervision of the attending physician.

Overdose

Acute overdose is unlikely, however, with excessive or prolonged use of the drug, a chronic overdose is possible, accompanied by signs of hypercorticism: hyperglycemia, glucosuria, reversible suppression of the adrenal cortex, manifestation of Cushing’s syndrome.

Treatment. Appropriate symptomatic treatment is indicated. In case of chronic toxic effects, gradual discontinuation of the drug is recommended.

Special instructions

The drug is not used in ophthalmology. Avoid contact with eyes, damaged skin, and open wound areas. In order to increase the effectiveness of therapy, it is possible to use occlusive dressings. It should be taken into account that this increases the transdermal absorption of betamethasone and gentamicin, which leads to an increased risk of systemic side effects.

If a stable bacterial or fungal microflora appears, the drug should be discontinued and appropriate therapy should be prescribed. it is possible to develop cross-resistance with aminoglycoside antibiotics.

Product form

Cream.

Storage conditions

At a temperature of 15-25 °C.

Shelf

life is 2 years.

Active ingredient

Betamethasone, Gentamicin

Dosage form

cream

Description

Children over 2 years of age, Children prescribed by a doctor, Pregnant women prescribed by a doctor, For adults

Indications

Dermatosis, Psoriasis, Dermatitis, Eczema, Diaper Rash, Allergy