Composition
of 1 tab. | |
gamma-aminobutyric acid | 250 mg |
Pharmacological action
Gamma-aminobutyric acid (GABA, gamma-aminobutyric acid) is a biogenic amine that restores the processes of metabolism in the brain, promotes the utilization of glucose by the brain and the removal of toxic metabolic products from it, and normalizes the dynamics of nervous processes in the brain. Increases the productivity of thinking, improves memory, has a mild psychostimulating effect, favorably affects the restoration of movement and speech after a violation of cerebral circulation. Helps to reduce and stabilize high blood pressure and reduce subjective symptoms of arterial hypertension (dizziness, sleep disorders). It has moderate antihypoxic and anticonvulsant effects. In patients with diabetes mellitus, it reduces the glucose content; with normal blood glucose content, it has the opposite effect (due to glycogenolysis). Pharmacokineticabsorption is fast and fairly complete. Cmax in blood plasma is reached after 60 minutes, then the concentration decreases rapidly. After 24 hours, GABA is not detected in the blood plasma.
Indications
Conditions after suffering disorders of cerebral circulation; after traumatic brain injuries. Atherosclerosis of cerebral vessels with signs of softening of the brain. Alcoholic encephalopathy and polyneuritis. Headache, dizziness, sleep disorders in hypertension. Infantile cerebral palsy; consequences of craniocerebral and birth trauma in children; mental retardation in children; kinetoses.
Contraindications
Hypersensitivity to GABA.
Side effects
Possible: nausea, vomiting, lability of blood pressure, dyspepsia, fever, sleep disorders.
Interaction
With simultaneous use, it is possible to increase the effect of benzodiazepine derivatives, many sleeping pills and antiepileptic drugs.
How to take, course of use and dosage
The daily dose for adults is 3-3.75 g. Children aged 1 to 3 years – 1-2 g / day; from 4 to 6 years-2-3 g/day; older than 7 years-3 g/day. The daily dose for children and adults is divided into 3 doses and taken before meals. The course of treatment lasts from 2-3 weeks to 2-4 months. For the prevention and treatment of kinetosis, adults – 500 mg 3 times/day for 3-4 days, children-250 mg 3 times/day for 3-4 days.
Special instructions
In the first days of treatment, blood pressure may fluctuate.
Active ingredient
Gamma-aminobutyric acid
Conditions of release from pharmacies
By prescription
Dosage form
Tablets
Description
Children as prescribed by a doctor, Adults as prescribed by a doctor
Indications
Low learning ability, Impaired cerebral circulation, Concussion and other traumatic brain injuries, Prevention of heart attacks and strokes, Alcoholism, Consequences of stroke
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