Angiorus pills 50mg+450mg, 60pcs

Composition

Active ingredients: hesperidin-50 mg, diosmin-450 mg.

Excipients: hypromellose (oxymethylpropylcellulose) – 6.5 mg, lactose monohydrate (milk sugar) – 42 mg, talc-22.8 mg, magnesium stearate-7.6 mg, sodium carboxymethyl starch (sodium starch glycolate) – 22.8 mg, microcrystalline cellulose-158.3 mg.

Shell composition: opadray II yellow – 22.8 mg.

The composition of opadraya II yellow: macrogol-4000 (polyethylene glycol-4000) – 4.6056 mg, titanium dioxide-1.6188 mg, talc -3.3744 mg, polyvinyl alcohol-9.100 mg, iron dye oxy yellow-4.0812 mg

Pharmacological action

Pharmacodynamics . It has venotonizing and angioprotective properties. The drug reduces the dilatability of veins and venous congestion, reduces the permeability of capillaries and increases their resistance, improves microcirculation and lymph outflow. When used systematically, it reduces the severity of clinical manifestations of chronic venous insufficiency of the lower extremities of organic and functional nature.

Pharmacokinetics.

The main elimination of the drug occurs through the intestines. On average, about 14% of the amount of the drug taken is excreted by the kidneys. The elimination half-life is 11 hours.

The drug undergoes an active metabolism, which is confirmed by the presence of phenolic acids in the urine.

Indications

Treatment of symptoms of venous-lymphatic insufficiency:

• – pain;
• – cramps of the lower extremities;
• – feeling of heaviness and bursting in the legs;
• -” fatigue ” of the legs.

Treatment of venous-lymphatic insufficiency manifestations:

• – edema of the lower extremities;
• – trophic changes in the skin and subcutaneous tissue;
• – venous trophic ulcers.

Symptomatic treatment of acute and chronic hemorrhoids.

Use during pregnancy and lactation

Animal experiments did not reveal any teratogenic effects.

To date, there have been no reports of adverse effects when using the drug in pregnant women.

Due to the lack of data on the excretion of the drug in breast milk, it is not recommended to take the drug during breastfeeding.

Reproductive toxicity studies have shown no effect on reproductive function in rats of both sexes.

Contraindications

Hypersensitivity, breast-feeding period.

Patients with rare hereditary problems such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption syndrome.

Side effects of

the Frequency of occurrence of adverse reactions is given in accordance with the who classification: very often (>1/10); often (>1/100, <1/10 ); infrequently (>1/1000, <1/100); rare (>1/10 000, <1/1000); very rare (<1/10 000, including individual messages); frequency unknown (frequency cannot be estimated according to the available data).

From the central nervous system:

Rarely: dizziness, headache, general malaise.

From the digestive system:

Common: diarrhea, dyspepsia, nausea, vomiting. Infrequently: colitis.

Frequency unknown: abdominal pain.

Allergic reactions:

Rare: skin rash, pruritus, urticaria.

Frequency unknown: isolated swelling of the face, lips, and eyelids. In exceptional cases, angioedema.

Inform your doctor if you have any adverse reactions or sensations, including those not mentioned in these instructions, as well as changes in laboratory parameters during therapy.

Interaction

There are no data on interactions with other drugs.

You should inform your doctor about all medications you are taking.

How to take, course of use and dosage

Inside, during a meal.

For venous-lymphatic insufficiency – 2 tablets per day (in one or two doses): in the morning, afternoon, and / or evening.

The duration of the course of treatment can be several months (up to 12 months). In case of recurrent symptoms, the course of treatment may be repeated on the doctor’s recommendation.

For acute hemorrhoids – 6 tablets per day: 3 tablets in the morning and 3 tablets in the evening for 4 days, then 4 tablets per day: 2 tablets in the morning and 2 tablets in the evening for the next 3 days.

The recommended dose for chronic hemorrhoids is 2 tablets per day.

Special instructions

Before starting to take the drug ANGIORUS, it is recommended to consult a doctor.

In case of acute hemorrhoids, the use of ANGIORUS does not replace the specific treatment of other anal disorders. The duration of treatment should not exceed the time specified in the section “Dosage and use”. If the symptoms do not disappear after the recommended course of therapy, a proctological examination should be performed and the therapy used should be reviewed.

In the presence of venous circulatory disorders, the maximum effect of treatment is provided by combining therapy with a healthy (balanced) lifestyle: it is advisable to avoid long exposure to the sun, long stay on your feet, and it is also recommended to reduce excess body weight. Hiking and, in some cases, wearing special stockings that help improve blood circulation.

Contact your doctor immediately if your condition worsens or does not improve during treatment.

Influence on the ability to drive vehicles and mechanisms

It doesn’t affect you.

Storage conditions

In a place protected from light, at a temperature not exceeding 30 °C. Keep out of reach of children.

Shelf

life is 2 years.

Active ingredient

Hesperidin, Diosmin

Dosage form

Tablets

Description

For adults

Indications

Hemorrhoids, Varicose veins, Trophic ulcers