ATC code | C09CA04 |
---|---|
CAS Number | 138402-11-0 |
Other product names | Irbesartan |
Dosage form | Tablets, film-coated |
Active ingredient | Irbesartan |
Other ingredients | Lactose monohydrate, microcrystalline cellulose, pregelatinised starch, sodium stearyl fumarate, hypromellose, titanium dioxide, macrogol 400, iron oxide yellow, iron oxide red |
Pharmacological classification | Angiotensin II receptor antagonist |
Pharmacological action | Reduces blood pressure, slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes |
Storage conditions | Store below 25°C, protect from moisture |
Aprovel: What It Is and How It Works
Aprovel is a medication classified as an angiotensin-II receptor antagonist. Angiotensin-II is a chemical naturally produced in your body that binds to receptors in your blood vessels, causing them to constrict. This leads to an increase in blood pressure. Aprovel prevents angiotensin-II from attaching to these receptors, allowing your blood vessels to relax and your blood pressure to decrease.
Imagine your blood vessels as garden hoses. When you pinch the hose, the water pressure increases. Aprovel works by preventing the pinch, allowing the water to flow freely, just like it releases your blood vessels and lowers your blood pressure.
What is Aprovel?
- Each Aprovel tablet contains 300 mg of irbesartan, the active ingredient that helps reduce blood pressure.
Benefits and Risks of Aprovel
Advantages
- Reducing blood pressure: Aprovels primary benefit lies in significantly lowering high blood pressure, a major risk factor for kidney disease, heart disease, and stroke.
- Protecting kidneys in type 2 diabetes: Aprovel can help individuals with type 2 diabetes and high blood pressure safeguard their kidneys from damage caused by the condition.
What is Aprovel Used For?
Aprovel is used to treat:
- Essential hypertension: The most common type of high blood pressure where the cause is unknown.
- High blood pressure and type 2 diabetes: Aprovel is used in conjunction with other medications to control blood pressure and protect the kidneys in patients with type 2 diabetes.
How to Use Aprovel
Follow your doctors instructions carefully when using Aprovel. The standard dosage is typically 150 mg once a day, although your doctor may adjust the dosage based on your individual needs. Aprovel can be taken with or without food. Swallow the tablet whole with a glass of water.
Dosage and Administration of Aprovel
The typical starting dosage for Aprovel is 150 mg once a day. Your doctor may increase the dosage to 300 mg once daily if your blood pressure is not adequately controlled. It may take four to six weeks after starting the medication to achieve the maximum blood pressure-lowering effect.
Side Effects of Aprovel
Like all medications, Aprovel can have side effects, although not everyone experiences them. Some side effects may be serious and require immediate medical attention. Common side effects include dizziness, nausea or vomiting, fatigue, and elevated levels of creatine kinase, an enzyme that indicates muscle and heart activity. Less common side effects include coughing, diarrhea, indigestion or heartburn, sexual dysfunction, chest pain, flushing, and increased heart rate.
Contraindications for Aprovel
Aprovel may not be suitable for everyone. You should not use Aprovel if you are allergic to irbesartan or any other ingredient in Aprovel, or if you are pregnant more than three months.
It is also recommended to avoid Aprovel during early pregnancy. If you are pregnant or breastfeeding, discuss the risks and benefits of using Aprovel with your doctor.
Storage of Aprovel
Store Aprovel at room temperature, away from heat and moisture. Keep it out of reach of children. Do not use Aprovel after the expiration date printed on the package.
Important Information About Aprovel
- Inform your doctor if you are also taking vitamins, herbal supplements, over-the-counter medications, or other prescription drugs.
- Tell your doctor if you have any pre-existing medical conditions, such as kidney or heart problems, or if you are scheduled for surgery.
- Consult your doctor before using Aprovel if you are pregnant, think you may be pregnant, or are planning to become pregnant.
- Nursing mothers should not use Aprovel.
- Contact your doctor immediately if you experience any unusual side effects or symptoms while taking Aprovel.
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