Arpeflu pills 50mg 30pcs

Composition

Active ingredient:  

ethyl ether 6-bromo-5-hydroxy-1-methyl-4-dimethylaminomethyl-2-phenylthiomethylindol-3-carboxylic acid hydrochloride monohydrate-50 mg

Pharmacological action

Antiviral agent, has an immunomodulatory and anti-influenza effect, specifically suppresses influenza A and B viruses.

It has interferoninducing properties, stimulates humoral and cellular immune responses, phagocytic function of macrophages, and increases the body’s resistance to viral infections. It prevents the development of post-influenza complications, reduces the frequency of exacerbations of chronic diseases, and normalizes immunological parameters.

The antiviral effect is due to the suppression of the fusion of the lipid envelope of the virus with cell membranes when the virus comes into contact with the cell. Therapeutic efficacy in influenza is manifested in a decrease in intoxication and the severity of catarrhal phenomena, shortening of fever periods and the overall duration of the disease.

It is classified as low-toxic medicinal products ( LD 50>4 g / kg). It does not have any negative effects on the human body when administered orally at the recommended doses.

Pharmacokinetics

Absorption is fast. Quickly distributed to organs and tissues. TSMACH when taken at a dose of 50 mg – 1.2 hours,100 mg – 1.5 hours is metabolized in the liver. T1 / 2 – 17-21 hours About 40% is excreted unchanged, mainly in the bile (38.9%) and in a small amount by the kidneys (0.12%). During the first day,90% of the administered dose is removed.

Indications

Treatment and prevention of influenza and other acute respiratory infections (including those complicated by bronchitis and pneumonia); chronic bronchitis, pneumonia, recurrent herpetic infection (in complex treatment); for the prevention of infectious complications and normalization of the immune status in the postoperative period.

Contraindications

• Hypersensitivity;
• children’s age (up to 3 years);
• presence of diseases such as galactose intolerance, lactase deficiency, glucose-galactose malabsorption.

Side effects

Allergic reactions.

Interaction

When prescribed with other drugs, no negative effects were observed.

How to take, course of use and dosage

Inside, before meals. Single dose:  children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg (2 tablets of 100 mg or 4 tablets of 50 mg).

For non-specific prevention

In direct contact with patients with influenza and other acute respiratory viral infections:  children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg once a day for 10-14 days.

During the epidemic of influenza and other acute respiratory viral infections, to prevent exacerbations of chronic bronchitis, relapse of herpetic infection:  children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 2 times a week for 3 weeks.

Prevention of postoperative complications:  children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 2 days before surgery, then on the 2nd and 5th days after surgery.

For treatment purposes

Flu, other acute respiratory infections without complications:  children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 4 times a day (every 6 hours) for 5 days.

Flu, other acute respiratory infections with the development of complications (bronchitis, pneumonia, etc. ):  children from 3 to 6 years – 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 4 times a day (every 6 hours) for 5 days, then a single dose once a week for 4 weeks.

Special instructions

It does not show central neurotropic activity and can be used in medical practice for preventive purposes in practically healthy people of various professions, including those requiring increased attention and coordination of movements (transport drivers, operators, and so on).

Form of production

Pills.

Active ingredient

Umifenovir

Dosage form

Tablets

Description

Children as prescribed by a doctor, Children over 3 years of age, For adults

Indications

for acute respiratory viral infections, Flu, Prevention of flu and colds, Shingles, Colds, Herpes