ATC code | G02CX01 |
---|---|
CAS Number | 117927-04-9 |
Other product names | Tractocile, Antocin, RWJ 22164 |
Dosage form | Concentrate for solution for infusion |
Active ingredient | Atosiban (as acetate) |
Other ingredients | Mannitol, hydrochloric acid 1M and water for injections |
Pharmacological classification | Tocolytic |
Pharmacological action | Inhibitor of oxytocin and vasopressin |
Storage conditions | Store in a refrigerator (2°C to 8°C). |
Atosiban Concentrate 7.5 mg/mL 5 mL 1 pc: Postponing Premature Labor
Atosiban Concentrate 7.5 mg/mL (5 mL, 1 pc) is used to postpone premature labor in expecting mothers. It acts by preventing the activity of oxytocin, a hormone triggering uterine contraction. This drug must be diluted before being injected since it is sold as a concentrate for a solution for infusion.
Atosiban Concentrate Composition
Atosiban (as acetate) in each 5 mL vial of Atosiban Concentrate amounts to 37.5 mg. Every milliliter of the concentrate has 7.5 mg of atosiban. The atosiban concentration in the final infusion solution following dilution is 0.75 mg/mL.
Benefits and Effects of Atosiban Concentrate
Professionals in the medical field find great use for Atosiban Concentrate in controlling preterm delivery. Reducing the activity of oxytocin helps to postpone the start of labor and maybe lets the fetus develop farther in the womb. Improved results for the mother and the child can follow from this.
Who Can Use Atosiban Concentrate?
Particularly for those showing severe clinical symptoms of imminent preterm birth, Atosiban Concentrate is especially indicated for usage in pregnant women who run the risk of preterm labor. Usually prescribed to women between 24 and 33 weeks of gestation who have not yet had preterm rupture of membranes, this drug
Administering Atosiban Concentrate
Only certified healthcare professionals working in a hospital or clinical environment should administer Atosiban Concentrate. Carefully follow the dosage and administration directions given by your pharmacist or doctor.
Dosage and Administration
The particular patient and their clinical situation will affect the Atosiban Concentrate dosage. Usually, the drug is given as a loading dosage, then maintained by an infusion. Usually for three hours, the loading dose is 24 mL/hour (18 mg/h); the maintenance infusion is administered at a rate of 12 mL/hour (9 mg/h). The reaction of the patient to treatment will affect the length of the infusion.
Potential Side Effects
Atosiban Concentrate might have adverse effects, just like any drug. Some typical side effects consist in:
- Pain in the head
- Apprehension
- Pertussiveness
- Colitis
- Clearing
- Blood pressure rising
Also, rare but rather severe adverse effects can arise. Tell your doctor straight away if you have any unexpected or worrying symptoms while using Atosiban Concentrate.
Contraindications
Not all pregnant ladies will find Atosiban Concentrate appropriate. In the following circumstances, it is contraindicated:
- Gestational age is either fewer than 24 weeks or more than 33 full weeks.
- Premature membrane rupture occurring at 30 weeks of gestation or beyond
- Known to be particularly sensitive to atosiban or any of the excipients
- Severe pre-eclampsia
- Active vaginal bleeding-through
- Abruption of the placenta
- Fetal agony
- Infection in the uterus
Before starting Atosiban Concentrate, you should be sure your healthcare professional reviews your medical history and any possible contraindications.
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Side effects of Atosiban concentrate 7.5mg/ml 5ml, 1pc
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