Benfogamma 150 pills, 60pcs

Composition

Active ingredient:  benfotiamine 150 mg; Excipients:  MCC-122 mg; povidone K 30-8 mg; fatty acid glycerides-5 mg; colloidal silicon dioxide-7 mg; sodium carmellose-3 mg;talc — 10 mg; Shell:  shellac — 3 mg; sucrose — 70,875 mg; calcium carbonate 66,479 mg; talc — 41,314 mg; acacia gum 10,155 mg; corn starch — of 7.34 mg; titanium dioxide — 10,932 mg; silicon dioxide colloidal — 4,404 mg; povidone 30 of 6.21 mg; macrogol 6000 — 1,555 mg; glycerol 85% — 2,262 mg; Polysorbate 80 — a of 0.133 mg; wax mountain glycol — 0.3 mg.

Pharmacological action

Vitamin preparation. Benfotiamine is a fat-soluble derivative of thiamine (vitamin B1). Thiamine is converted to active thiamine pyrophosphate and as a coenzyme is included in the pyruvate decarboxylase, alpha-ketoglutarate decarboxylase complexes, which are involved in the oxidative decarboxylation of pyruvic and alpha-ketoglutaric acids; transketolase is an enzyme of the pentose phosphate shunt.

Indications

Vitamin B1 deficiency, confirmed by clinical and biochemical studies, developing against the background of:

— insufficient and inadequate nutrition (Beriberi disease);

– parenteral nutrition for a long time;

– hemodialysis;

– chronic alcoholism (alcoholic cardiomyopathy, Wernicke’s encephalopathy, Korsakov’s syndrome);

— increased need for vitamin B 1.

Polyneuropathies caused by vitamin B 1 deficiency. Typical signs of such a deficiency are neurological disorders in the form of neuropathies with sensory disturbances (pain, tingling, loss of sensitivity in the upper and lower extremities).

Contraindications

-sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption;

– pregnancy;

– childhood;

– increased individual sensitivity to the components of the drug.

Side effects

Allergic reactions:  angioedema, urticaria, pruritus of the skin.

Interaction

Thiamine weakens the effect of depolarizing muscle relaxants (suxamethonium iodide and others), and is inhibited by fluorouracil.

Ethanol slows down the rate of absorption of thiamine after oral use.

How to take, course of use and dosage

For the treatment of vitamin B 1 deficiency is prescribed for 1 tab. 1 time / day

For the treatment of polyneuropathies caused by vitamin B 1 deficiency, the initial dose is 1 tab. 2 times / day for 3 weeks, then assign 1 tab. daily.

The duration of treatment depends on its effectiveness and is determined by the doctor.

The tablet is taken without chewing, washed down with a small amount of water.

Overdose

No overdose of Benfogamma 150 has been reported so far.

Special instructions

No adverse reactions other than those mentioned above were observed in the elderly.

It is not recommended to take a double dose of the drug if the previous dose was missed.

In Wernicke’s encephalopathy, the use of dextrose should be preceded by thiamine.

Influence on the ability to drive vehicles and mechanisms

There are no data on the effect of the drug used in therapeutic doses on the ability to drive vehicles and mechanisms.

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

5 years

Active ingredient

Benfotiamine

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Indications

Polyneuropathy, Malnutrition, Alcoholism