Braunodin B. Brown ointment for external use 10%, 20g

Composition

Active ingredient:

povidone-iodine (with an active iodine content of 10%) 10.0 g

Pharmacological action

Antiseptic agent, which is a complex of iodine and povidone, effective at pH from 2 to 7.

The bactericidal effect is caused by free active iodine, which is released from the povidone-iodine complex.

In comparison with alcohol-containing solutions of iodine, an aqueous solution of povidone-iodine has a significantly lower irritant effect.

Free iodine, as a strong oxidizer, reacts at the molecular level with insoluble fatty acids and practically non-oxidizing SH-and OH-groups of amino acids in the composition of enzymes and the main structural components of gram-positive and gram-negative bacteria, mycobacteria, fungi, especially the genus Candida, various viruses and some protozoa.

However, for complete inactivation of some viruses and bacterial spores, a fairly long period of drug exposure is required. There are no known cases of resistance in microorganisms with prolonged use of povidone-iodine.

Indications

Post-traumatic and post-operative wounds of various localization, burns, trophic ulcers, bedsores.

Skin infections of various etiologies, including infectious dermatitis and eczema.

Damage to the skin of various origins (maceration, abrasions, bruises).

Contraindications

Hypersensitivity to the components of the drug. Disorders of the thyroid gland (thyrotoxicosis). Thyroid adenoma. Duhring’s herpetiform dermatitis.

Simultaneous use of radioactive iodine. Preterm infants, newborns, and children under 6 months of age.

Side effects

Hypersensitivity reactions to the drug are possible: delayed-type allergic reactions (itching, redness of the skin, blisters) or immediate-type allergic reactions (anaphylactoid reactions).

Prolonged use of the drug (more than 7-10 days) and application to large skin surfaces, extensive wounds due to absorption can cause phenomena of iodism (“metallic” taste in the mouth, increased salivation and lacrimation, swelling of the mucous membranes) and systemic reactions (metabolic acidosis, hyponatremia, impaired renal and thyroid function), if they occur, stop using the drug and consult a doctor.

Interaction

The drug is incompatible with alkaloid salts (celandine), tannic acid (tannin), salicylic acid, silver salts, bismuth, taurolidine and hydrogen peroxide. In the presence of blood and pus, the drug binds to proteins and other organic compounds, as a result of which its bactericidal activity may decrease.

In this case, it is recommended to increase the frequency of its use. Concomitant use of povidone-iodine and topical preparations containing enzymes may contribute to the oxidation and suppression of their enzymatic activity.

Povidone-iodine has a synergistic effect with lithium preparations, as a result of which, if they are used together for a long time, reversible inhibition of thyroid function is possible. Therefore, patients who are constantly taking lithium preparations should avoid prolonged application of povidone-iodine on large surfaces.

The drug can lead to false-positive results in some diagnostic tests: determination of hemoglobin or sugar in the urine and stool, examination of thyroid function, etc. Examination of the thyroid gland in this case should be carried out no earlier than 1-2 weeks after the end of povidone-iodine treatment.

How to take, course of use and dosage

Externally. The drug is applied to the affected surface from one to several times a day until the symptoms of inflammation disappear.

If necessary, use bandages, gauze swabs and turundas. The frequency and duration of application of the ointment depends on the course of the wound process.

The course of treatment is 5-10 days.

Overdose

If iodine is absorbed intensively over a long period of time, the following symptoms may occur: tachycardia, agitation, trembling, and headache.

In this case, you should immediately stop using the drug and consult a doctor.

Form of production

Ointment.

Storage conditions

Store in a place protected from light and out of reach of children at a temperature of 2 to 25 ° C.

Active ingredient

Povidone-Iodine

Dosage form

ointment

Description

For adults

Indications

Minor Skin injuries, Trophic Ulcers, Burns, Bedsores, Wounds, Pyoderma