ATC code | L02AE01 |
---|---|
CAS Number | 74441-54-6 |
Other product names | Suprefact, Suprefact Depot 2 Months, Suprefact Depot 3 Months |
Dosage form | Lyophilizate for suspension for intramuscular administration of prolonged action |
Active ingredient | Buserelin |
Other ingredients | Sodium chloride, sodium dihydrogen phosphate, sodium |
Pharmacological classification | Gonadotropin-releasing hormone analog |
Pharmacological action | Stimulates the pituitary glands gonadotrophin-releasing hormone receptor (GnRHR), Desensitizes the GnRH receptor, reducing the amount of gonadotropin, In males, this results in a reduction in the synthesis and release of testosterone, In females, estrogen secretion is inhibited, While initially, there is a rise in FSH and LH levels, chronic administration of Buserelin results in a sustained suppression of these hormones |
Storage conditions | Store at room temperature, Protect from light |
Buserelin-long Lyophilizate 3.75 mg
Buserelin-long lyophilizate 3.75 mg is a synthetic counterpart of naturally occurring gonadotropin-releasing hormone (GnRH). It is available as a lyophilizate, which is a powder that must be reconstituted using a solvent prior to usage.
Uses
Buserelin-long is used to treat a variety of disorders, including:
- Endometriosis
- Uterine fibroids
- Prostate cancer
- Premenopausal breast cancer
- Early puberty
- Transgender hormone treatment
How it Works
Buserelin-long treatments reduce the synthesis of hormones that promote the development of specific tissues, including those of the prostate and uterus, therefore inhibiting their growth. This effect is obtained by simulating the action of GnRH, therefore lowering the levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Composition
Buserelin-long Lyophilizate 3.75 mg vial has 3.75 mg of buserelin acetate. The following are among the additional components:
- Mannitol
- Carmellose sodium
- Polysorbate-80
- DL-lactic and glycolic acid copolymers
Dosage and Administration
Buserelin-long Lyophilizate 3.75 mg is usually prescribed as 3.75 mg given intramuscular injection once every 4 weeks. The particular patient and the ailment under treatment will affect the dosage and frequency of administration. You should pay great attention to your doctors directions.
Side Effects
Buserelin-long Lyophilizate 3.75 mg has side effects, just like all drugs. Some typical side effects include:
- Heat flashes
- Variations in mood
- Vaginal dryness
- Decreased libido
- Bone loss
- Weight gain
Contraindications
Buserelin-long Lyophilizate 3.75 mg should not be used if you have a buserelin allergy or any other pharmaceutical allergy. Furthermore, avoid using this drug if you have any medical disorders, such as:
- Pregnancy
- Breastfeeding
- Severe liver disease
- Severe kidney disease
Storage
Store Buserelin-long Lyophilizate 3.75 mg refrigerated between 2 and 8 °C. Protect from light and moisture. Keep out of reach of children.
Purchase
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Understanding Buserelin-long
Buserelin-long, a synthetic hormone, works by mimicking the natural hormone GnRH. This action tricks the body into thinking it has already released enough GnRH, leading to a decrease in the production of other hormones like FSH and LH. These hormones are responsible for stimulating the growth of certain tissues, including those in the prostate, uterus, and breasts. By reducing the levels of FSH and LH, Buserelin-long effectively slows down or stops the growth of these tissues, making it a valuable treatment for various conditions.
Important Considerations
While Buserelin-long offers a promising approach to managing these conditions, its important to remember that it is a prescription medication. Its crucial to consult with a healthcare professional before starting any new treatment, especially one involving hormones. Your doctor will assess your individual medical history, current health status, and potential risks before determining if Buserelin-long is suitable for you. They will also advise on the appropriate dosage and administration method, ensuring optimal results while minimizing the chances of side effects.The information provided here is for general knowledge and informational purposes only and does not constitute medical advice. It is essential to seek the guidance of a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.
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