Calcemin Advance, pills, 30pcs

Composition

Active ingredients:

calcium (calcium citrate and calcium carbonate) 500 mg,

colecalciferol (vitamin D 3) 200 IU,

magnesium 40 mg,

zinc 7.5 mg,

copper 1 mg,

manganese 1.8 mg,

boron 250 mcg.

Auxiliary substances:

maltodextrin 25 mg,

microcrystalline cellulose 49.05 mg,

sodium croscarmellose 38 mg,

stearic acid 16.3 mg,

soy polysaccharide 15 mg,

sodium lauryl sulfate 5 mg.

Shell:

polymer 26,328 mg,

titanium dioxide 12,643 mg,

magnesium silicate,5 mg,

triacetin 5,689 mg,

mineral oil 2,845 mg,

dye red No. 40 (dye enchanting red) 0,316,

dye yellow No. 6 (sunset yellow) 0,079 mg,

dye blue No. 1 0,04 mg

Pharmacological action

Calcemin advance is a drug with enhanced formula, which contains vitamin D3 and minerals for the prevention of bone fragility and complex treatment of osteoporosis. With age, calcium is washed out of the bones, and they become brittle. Unlike other calcium supplements (3), Calcemin Advance contains special minerals (magnesium, zinc, manganese, copper, boron) to form a collagen network that keeps calcium in the bone, preventing it from leaching out(4). Calcemin Advance is applied:  – for the prevention and comprehensive treatment of osteoporosis; – to improve the healing of fractures;- to make up for the lack of calcium and trace elementscalcemin Advance – so that the bones remain strong!

Indications

Prevention and comprehensive treatment of osteoporosis of various origins:  

– in women during menopause (natural and surgical)–

– in people who take corticosteroids and immunosuppressants for a long time.

Treatment of diseases of the musculoskeletal system ( to improve the consolidation of traumatic fractures)

To compensate for the lack of calcium and trace elements in adolescents.

Use during pregnancy and lactation

During pregnancy and lactation, the use of the drug should be agreed with your doctor.

the daily dose should not exceed 1500 mg of calcium and 600 IU of vitamin D3, hyperhalcemia that develops against the background of overdose during pregnancy can cause mental and physical development defects in the fetus.

In nursing women, it should be taken into account that colecalciferol and its metabolites pass into breast milk, so it is necessary to take into account the intake of calcium and vitamin D3.

Contraindications

Increased individual sensitivity to the components of the drug, vitamin D hypervitaminosis, hypercalcemia and hypercalciuria, severe renal failure, urolithiasis, nephroltiasis, active tuberculosis, sarcoidosis, children (up to 12 years), allergic reaction to peanut butter and soy, as the drug contains soy polysaccharide.

With caution:

Pregnancy and lactation, kidney failure.

Side effects

Nausea, vomiting, flatulence, diarrhea, constipation, hypercalcemia, hypercalciuria, allergic reactions (pruritus, rash, urticaria).

Interaction

Concomitant use of Calcemin with vitamin A reduces the toxicity of vitamin D3. Phenytoin, barbiturates, corticosteroids reduce the effectiveness of vitamin D3. Laxatives reduce the absorption of vitamin D3. Corticosteroids, hormonal contraceptives for systemic use, levothyroxine worsen the absorption of calcium ions.

With simultaneous use of tetracyclines, the interval between doses should be at least 3 hours, bisphosphonates and sodium fluoride (their absorption is impaired). — not less than 2 hours. With the combined use of Calcemin with cardiac glycosides, their toxicity increases (ECG and clinical condition monitoring is necessary), with thiazide diuretics-the risk of hypercalcemia increases, with furosemide and other loop diuretics-the excretion of calcium by the kidneys increases.

Calcemin should not be used simultaneously with calcium channel blockers. Concomitant use of the drug with antacids containing aluminum is not recommended due to a decrease in their effectiveness.

How to take, course of use and dosage

Take orally, with a meal.

Complex therapy of osteoporosis – 1 tablet 2 times a day.

Prevention of oseoporosis – 1 tablet per day.

When using the drug for the prevention and complex therapy of osteoporosis, the duration of treatment is determined by the doctor individually. The average duration of the course for prevention is 2 months, for the treatment of osteoporosis-3 months.

Treatment of diseases of the musculoskeletal system: to improve the consolidation of traumatic fractures-1 tablet per day, the duration of treatment is 4-6 weeks.

To compensate for the lack of calcium and trace elements in adolescents from 12 years of age-1 tablet per day. The average duration of treatment is 4-6 weeks.

Overdose

Vitamin D hypervitaminosis, hypercalcemia and hypercalciuria.

Symptoms: decreased appetite, thirst, polyuria, dizziness, fainting, constipation, nausea and vomiting, muscle weakness, headache, coma, fatigue, bone pain, mental disorders, nephrocalcinosis, abdominal pain, urolithiasis, in severe cases-cardiac arrhythmias.

With prolonged use in doses of more than 2500 mg of calcium – kidney damage, soft tissue calcification.

If the first signs of overdose are detected, it is necessary to reduce the dose or stop using the drug, consult a doctor.

In case of hypercalciuria exceeding 7.5 mmol/day (300 mg/day), the dose should be reduced or the drug should be discontinued.

Treatment: rehydration, loop diuretics (for example, furosemide), glucocorticosteroids, calcitonin, bisphosphonates, in severe cases, hemodialysis.

In case of accidental overdose, induce vomiting, flush the stomach. Therapy is symptomatic.

In this case, it is necessary to reduce the dose or stop using the drug. In case of accidental overdose, induce vomiting, flush the stomach. Therapy is symptomatic.

Special instructions

The dose should not exceed the one indicated in the instructions, since increased calcium intake can inhibit the absorption of iron, zinc and other essential minerals in the intestines.

Form of production

Coated tablets.

Storage conditions

In a dry place, at a temperature of 15-30 °C

Shelf life

3 years

Active ingredients

: Calcium Carbonate, Colecalciferol, Copper Oxide, Sodium Borate, Zinc oxide, Manganese Sulfate

Dosage form

Tablets

Indications

Calcium deficiency, Magnesium Deficiency, Osteoporosis, Menopause, Bone fractures