Calcium-D3 Nicomed pills chewable mint, 60pcs

Composition

1 tablet contains:

Calcium Carbonate 1250 mg (equivalent to elemental calcium 500 mg)

Colecalciferol (vit. D3) 5 mcg (200 IU) as colecalciferol concentrate Auxiliary substances:  

Sorbitol – 390 mg

Mint flavor supplement – 31.8 mg

Povidone – 36.4 mg

Magnesium Stearate – 6.00 mg

Aspartame-1.00 mg

Pharmacological action

A combined drug that regulates the exchange of calcium and phosphorus in the body (in bones, teeth, nails, hair, muscles). Reduces resorption (resorption) and increases bone density, making up for the lack of calcium and vitamin D3 in the body, which is necessary for the mineralization of teeth. Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood clotting system. Adequate calcium intake is especially important during growth, pregnancy, and lactation. Vitamin D3 increases the absorption of calcium in the intestines. The use of calcium and vitamin D3 prevents an increase in the production of parathyroid hormone, which is a stimulator of increased bone resorption (leaching of calcium from bones).

Indications

• Prevention and treatment of calcium and/or vitamin D3 deficiency;
• Prevention and complex therapy of osteoporosis and its complications (bone fractures).

Use during pregnancy and lactation

Calcium and vitamin D3 are used during pregnancy to make up for their deficiency in the body. During pregnancy, the daily dose of the drug should not exceed 1500 mg of calcium and 600 IU of vitamin D3. Hypercalcemia due to overdose during pregnancy can have an adverse effect on the developing fetus. The drug is used during lactation. Calcium and vitamin D3 can enter breast milk, so it is necessary to take into account the intake of calcium and vitamin D from other sources in the mother and child.

Contraindications

• Hypercalcemia
• Hypercalciuria
• Nephrolithiasis
• Hypervitaminosis D
• Severe renal failure
• Active form of tuberculosis
• Sarcoidosis
• Hypersensitivity to the components of the drug, soy or peanuts

The drug in tablet form is not used in children under 3 years of age.

The drug contains aspartame, which is converted to phenylalanine in the body, so the drug should not be taken with phenylketonuria.

The drug contains sorbitol, isomalt and sucrose, so its use is not recommended for patients with hereditary fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase insufficiency. With caution:  pregnancy, lactation, kidney failure.

Side effects

The frequency of side effects of the drug is estimated as follows: very frequent (>1/10); frequent (>>1/100,1/1000,1/10 000, From the side of metabolism and nutrition)infrequent – hypercalcemia, hypercalciuria. From the digestive system: rarely-constipation, flatulence, nausea, abdominal pain, diarrhea, dyspepsia. From the skin and subcutaneous tissue: very rarely-itching, rash, urticaria.

Interaction

Hypercalcemia may potentiate the toxic effects of cardiac glycosides when used concomitantly with calcium and vitamin D supplements. It is necessary to monitor the ECG and the content of calcium in the blood serum.

Calcium supplements may reduce the absorption of tetracyclines from the gastrointestinal tract. Therefore, tetracycline drugs should be taken at least 2 hours before or 4-6 hours after taking the drug.

To prevent a decrease in the absorption of bisphosphonate preparations, it is recommended to take them at least 1 hour before taking Calcium-D 3 Nicomed.

CORTICOSTEROIDS reduce the absorption of calcium, so treatment with corticosteroids may require an increase in the dose of Calcium-D3 Nicomed.

Concomitant use of thiazide-type diuretics increases the risk of hypercalcemia, as they increase the tubular reabsorption of calcium. When using thiazide diuretics at the same time, the serum calcium content should be regularly monitored.

Calcium reduces the effectiveness of levothyroxine by reducing its absorption. The time interval between taking levothyroxine and Calcium-D3 Nicomed should be at least 4 hours. The absorption of quinolone antibiotics decreases when used concomitantly with calcium supplements. Therefore, quinolone antibiotics should be taken 2 hours before or 6 hours after taking Calcium-D3 Nicomed.

Intake of foods containing oxalates (sorrel, rhubarb, spinach) and phytin (cereals) reduces the absorption of calcium, so do not take Calcium-D 3 Nicomed for 2 hours after eating sorrel, rhubarb, spinach, cereals.

How to take, course of use and dosage

Tablets can be chewed or dissolved and taken with meals. Calcium-D3 for adults for the prevention of osteoporosis – 1 tab. 2 times / day; in the complex therapy of osteoporosis-1 tab. 2-3 times/day. To compensate for the lack of calcium and vitamin D, adults and children over 12 years of age – 1 tab. 2 times/day, children from 5 to 12 years-1-2 tablets/day, children from 3 to 5 years-dosage in accordance with the doctor’s recommendations.

Overdose

Symptoms:  

• Symptoms of hypercalcemia include anorexia, thirst, polyuria, muscle weakness, nausea, vomiting, constipation, abdominal pain, fatigue, bone pain, mental disorders, nephrocalcinosis, urolithiasis, and, in severe cases, cardiac arrhythmias.
• With prolonged use of excessive doses (over 2500 mg of calcium) – kidney damage, soft tissue calcification.

If symptoms of overdose are detected, the patient should stop taking calcium and vitamin D, as well as thiazide diuretics and cardiac glycosides, and consult a doctor.

Treatment:  

• gastric lavage
• replacement of fluid loss
• the use of “loop” diuretics (for example, furosemide), corticosteroids, calcitonin, bisphosphonates.

It is necessary to monitor the content of electrolytes in the blood plasma, kidney function and diuresis. In severe cases, it is necessary to measure the central venous pressure and monitor the ECG.

Special instructions

With long-term therapy, the content of calcium and creatinine in the blood serum should be monitored. Monitoring is especially important in elderly patients who are being treated with cardiac glycosides and diuretics, and in patients with an increased tendency to form kidney stones. In cases of hypercalcemia or signs of impaired renal function, the dose should be reduced or treatment should be discontinued. Vitamin D should be taken with caution in patients with renal insufficiency. In this case, it is necessary to monitor the content of calcium and phosphates in the blood serum. It is also necessary to consider the risk of soft tissue calcification. To avoid overdose, additional vitamin D supplementation from other sources should be considered. Calcium and vitamin D3 should be used with caution in immobilized patients with osteoporosis due to the risk of hypercalcemia. Concomitant use with antibiotics of the tetracycline or quinolone group is usually not recommended, or should be carried out with caution. Influence on the ability to drive motor vehicles and manage mechanicsthe product does not affect the ability to drive motor vehicles or work with technically complex mechanisms.

Form of production

Chewable tablets

Storage conditions

The drug should be stored in a tightly closed bottle, in a dry, inaccessible place for children at a temperature not exceeding 25°C.

Shelf

life is 3 years. Do not use after the expiration date.

Active ingredient

: Calcium carbonate, Colecalciferol

Dosage form

tablets for resorption

Indications

Strengthen your Bones, Improve Your Cardiovascular System, Grow Your Hair and Strengthen your Nails