Calcium gluconate pills 500mg Renewal, 40pcs

Composition

Per tablet: Active ingredient: calcium gluconate monohydrate-0.5 gh auxiliary substances: potato starch-0.0194 g zinc-0.0053 g calcium stearate-0.0053 g

Pharmacological action

The preparation of calcium ions makes up for the lack of calcium ions necessary for the transmission of nerve impulses, contraction of skeletal and smooth muscles, myocardial activity, bone formation, blood clotting. Pharmacokinetics Approximately 1/5-1/3 of the ingested calcium gluconate is absorbed in the small intestine; this process depends on the presence of vitamin D, pH, dietary characteristics, and the presence of factors that can bind calcium ions. The absorption of calcium ions increases with its deficiency and a diet with a reduced content of calcium ions. About 20% is excreted by the kidneys, the remaining amount (80%) by the intestines (actively released by the wall of the terminal gastrointestinal tract).

Indications

Hypofunction of the parathyroid glands (latent tetany, osteoporosis), impaired vitamin D metabolism: rickets (spasmophilia, osteomalacia), hyperphosphatemia in patients with chronic renal failure. A condition that is accompanied by an increased need for calcium (during pregnancy, unbalanced and inadequate nutrition). Chronic intoxication with magnesium salts, oxalic and hydrofluoric acids and their soluble salts (when interacting with calcium gluconate, insoluble salts and non-toxic calcium oxalate and calcium fluoride are formed). Hyperkalemic form of paroxysmal myoplegia.

Contraindications

Hypersensitivity to the components of the drug, hypercalcemia (calcium concentration should not exceed 12 mg% = 6 mEq/L), hypercalciuria, nephrourolithiasis (calcium), sarcoidosis, intoxication with cardiac glycosides (risk of arrhythmias), severe renal failure, a tendency to thrombosis. Children under 5 years of age. With caution: Dehydration, electrolyte disturbances (risk of hypercalcemia), diarrhea, malabsorption syndrome, mild hypercalciuria, moderate chronic renal failure, chronic heart failure, advanced atherosclerosis, hypercoagulation, chronic diseases of the gastrointestinal tract, a history of calcium nephrourolithiasis.

Side effects

Allergic reactions, constipation, irritation of the gastrointestinal mucosa, nausea, vomiting, diarrhea, upper abdominal pain.

Interaction

Reduces the pharmacological effects of slow calcium channel blockers. When used concomitantly with quinidine, it is possible to slow down intraventricular conduction and increase the toxicity of quinidine. It slows down the absorption of tetracyclines, digoxin, and oral iron preparations (the interval between their use should be at least 2 hours). When combined with thiazide diuretics, it can increase hypercalcemia, reduce the effect of calcitonin in hypercalcemia, and reduce the bioavailability of phenytoin.

How to take, course of use and dosage

Inside, before taking or 1-1.5 hours after a meal (with milk), adults – 1-3 g (2-6 tablets) 2-3 times a day. Children from 5 to 6 years – 2-3 tablets (1-1.5 g); from 7 to 9 years-3-4 tablets (1.5-2 g); from 10 to 14 years – 4-6 tablets (2-3 g). Take 2-3 times a day.

Overdose

Symptoms:  hypercalcemia. Treatment:  to eliminate it,5-10 IU/kg/day of calcitonin is administered (diluted in 0.5 liters of 0.9% sodium chloride solution). The duration of use is 6 hours.

Storage conditions

In a dry place at a temperature not exceeding 25 °C. Keep out of reach of children.

Shelf

life is 5 years.

Active Ingredient

Calcium Gluconate