Cephalexin, capsules 500mg, 16pcs

Composition

Active ingredient:

Cephalexin – 500 mg (in the form of cephalexin monohydrate 525.9 mg).

Auxiliary substances:

Magnesium stearate,

microcrystalline cellulose PH 102.

Capsule composition:

Titanium dioxide E 171,

Iron Oxide yellow dye E 172,

Iron Oxide black dye E 172,

Indigo carmine (Indigotin I) E 132,

Gelatin.

Pharmacological action

Cephalexin has an antibacterial, bactericidal effect.

Indications

Diseases of the upper and lower respiratory tract, urinary tract, skin, soft tissues, otitis media, osteomyelitis, endometritis, gonorrhea.

Use during pregnancy and lactation

It is possible if the expected effect of therapy exceeds the potential risk to the fetus.

Breast-feeding should be discontinued for the duration of Cephalexin treatment.

Contraindications

Hypersensitivity to cephalosporins and penicillins.

Side effects

Nervous system and sensory disorders: headache, dizziness, drowsiness, hallucinations (rare).

Cardiovascular and blood disorders (hematopoiesis, hemostasis): eosinophilia, reversible leukopenia, neutropenia, thrombocytopenia.

From the gastrointestinal tract: nausea, vomiting, dry mouth, loss of appetite, diarrhea, cholestatic jaundice, hepatitis, transient increase in the activity of hepatic transaminases.

Allergic reactions: skin rash, pruritus, dermatitis, rarely-angioedema, arthralgia, candidiasis.

Interaction

When used concomitantly with furosemide, ethacric acid, or nephrotoxic antibiotics (for example, aminoglycosides), the risk of kidney damage increases.

Salicylates and Indometacin slow the elimination of cephalexin.

Reduces the prothrombin index, enhances the effect of indirect anticoagulants.

How to take, course of use and dosage

of Cephalexin is taken orally.

Adults: 250-500 mg 4 times a day.

Children: 25-50 mg/kg/day.

In case of severe infection: the daily dose of Cephalexin is increased for adults-up to 4 g (maximum), for children – up to 100 mg / kg and divided into 4 doses. The course of treatment is 7-14 days.

With a creatinine clearance of 10 ml / min, the maximum daily dose for adults is 1.5 g.

Overdose

Vomiting, nausea, epigastric pain, diarrhea, hematuria.

Treatment: activated charcoal (more effective than lavage), maintaining airway patency, monitoring vital functions, blood gases, and electrolyte balance.

Special instructions

Patients with a history of allergic reactions to penicillins and carbapenems may be hypersensitive to cephalosporin antibiotics.

During treatment with cephalexin, a positive direct Coombs reaction is possible, as well as a false positive reaction of urine to glucose.

During the treatment period, it is not recommended to use ethanol.

In staphylococcal infection, there is cross-resistance between cephalosporins and isoxazolylpenicillins.

Form of production

Capsules.

Storage conditions

In a dark place, at a temperature of 2-25°C.

Shelf

life is 3 years.

Active ingredient

Cephalexin

Conditions of release from pharmacies

By prescription

Dosage form

Capsules

Description

For adults as prescribed by a doctor, Pregnant women as prescribed by a doctor, Children as prescribed by a doctor, Children over 3 years of age

Indications

Urethritis, Bronchitis, Boils, Prostatitis, Otitis Media, Pyoderma, Sinusitis, Osteomyelitis, Tonsillitis, Pharyngitis, Sore Throat, Pneumonia, Inflammation of the female genital organs