Composition
Active ingredient: chlorhexidine bigluconate solution 20% – 2.5 ml (equivalent to 0.5 g of chlorhexidine bigluconate)Auxiliary substance: purified water-up to 1000 ml
Pharmacological action
Antiseptic agent, has a bactericidal effect against gram-positive and gram-negative bacteria, has a fungicidal and virucidal effect (against lipophilic viruses). It acts on bacterial spores only at elevated temperatures. It is effective against gram-positive and Gram-negative bacteria (including Treponema spp., Neisseria gonorrhoeae, Chlamydia spp. ), viruses and fungi. Pharmacokinetics: When applied externally to intact skin, it is practically not absorbed, when applied topically, it is not absorbed into the systemic circulation and does not have a systemic effect. It is practically not absorbed from the gastrointestinal tract. After accidental ingestion of 300 mg of the drug, the maximum blood concentration (Cmax) is reached in 30 minutes and is 0.206 mcg/l.
Indications
Prevention of sexually transmitted infections (chlamydia, ureaplasmosis, trichomoniasis, gonorrhea, syphilis, genital herpes-use no later than 2 hours after sexual intercourse); disinfection of the skin (scuffs, cracks). Purulent wounds, infected burns, bacterial and fungal diseases of the skin and mucous membranes, including in dentistry (rinsing and irrigation − gingivitis, stomatitis, aphthae, periodontitis, alveolitis), surgery, urology, obstetrics and gynecology.
Contraindications
Do not use in case of hypersensitivity to the components of the product, dermatitis.
Side effects
Allergic reactions (skin rash), dry skin, pruritus, dermatitis, sticky hands (within 3-5 minutes), photosensitization. In the treatment of gingivitis − staining of tooth enamel, tartar deposition, taste disorders. If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Interaction
It is used in a neutral environment; at pH 5-8, the difference in activity is small; at pH more than 8, precipitation occurs. The use of hard water reduces the bactericidal properties. Pharmaceutically incompatible with soaps, alkalis and other anionic compounds (colloids, gum arabic, carboxymethylcellulose). It is compatible with medicines containing a cationic group (benzalkonium chloride, cetrimonium bromide).
How to take, course of use and dosage
Externally. Locally. It is used in the form of irrigation, rinsing and applications-5-10 ml of the drug is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times a day (on a tampon or by irrigation). For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after sexual intercourse. Enter the contents of the bottle into the urethra: men (2-3 ml), women (1-2 ml) and in the vagina (5-10 ml) for 2-3 minutes. Treat the skin of the inner thighs, pubis, and genitals. After the procedure, do not urinate for 2 hours. Complex treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml into the urethra 1-2 times a day, the course is 10 days, the procedures are prescribed every other day.
Overdose
Currently, cases of overdose with external and topical application have not been reported; in case of accidental ingestion, it is practically not absorbed (gastric lavage should be performed using milk, raw egg, gelatin). If necessary, symptomatic therapy is performed.
Active ingredient
Chlorhexidine
Dosage form
solution for topical application
Description
For pregnant and lactating women, For adults
Indications
Disinfection, Burns, Minor Skin injuries, Sore Throat, Purulent Wounds, Wounds, Stomatitis, Fungus, Vaginitis, Female genital inflammation, Tonsillitis, Gum inflammation
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