Cinocap, aerosol 0.2%, 58g

Composition

Active ingredient:  

• zinc pyrithione (in terms of 100% substance) – 0.100 g;

excipients:  

• sodium lauryl sulfate – 0.050 g,
• methyl ethyl ketone – 33,500 g,
• silicon dioxide colloid (Aerosil) – 0,750 g
• dexpanthenol (D-Panthenol) – 0.300 g,
• Polysorbate-80 (tween-80) – 0,250 g,
• ethanol 70% (ethanol 70%) – 15,050 g,
• tetraborate (freon 134) – up to 58,000 G.

Pharmacological action

Pharmacotherapeutic group: dermatoprotective agent

ATX Code: D11AX12

Pharmacologicalproperties

Pharmacodynamics

Pyrithione zinc has anti-inflammatory, antibacterial and antifungal activity. The antibacterial activity of zinc pyrithione is manifested against a number of gram-positive and gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp. ).

Zinc pyrithione reduces the intracellular level of ATP, promotes depolarization of cell membranes, causing the death of fungi and bacteria. Antifungal activity is especially pronounced when acting on Pityrosporum ovale and Pityrosporum orbiculare, which cause inflammation and excessive peeling in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action has not been studied.

Pharmacokinetics

When applied externally, pyrithione zinc is deposited in the epidermis and the surface layers of the dermis. Systemic absorption is negligible. The drug is found in the blood in trace amounts.

Indications

• Psoriasis

• seborrheic dermatitis

• atopic dermatitis (eczema, atopic dermatitis) 

Contraindications

Hypersensitivity, children under 1 year of age.

Side effects

The drug is usually well tolerated. Sometimes there are allergic reactions.

How to take, course of use and dosage

The drug is intended for external use.

Apply in adults and children from 1 year.

Shake the container before use. Spray the drug on the affected area of the skin from a distance of about 15 cm for 3 seconds, while covering a surface equal to the area of the palm (which is equivalent to the consumption 1 ml of the drug). The affected area is treated 2-3 times a day until a clinical effect is achieved.

For treatment of the scalp with the drug, an additional nozzle is attached. It is advisable to continue using the drug for one week after the symptoms disappear.

Duration of treatment for:

• psoriasis 1-1.5 months, repeated courses-if signs of exacerbation appear;
• atopic dermatitis 3-4 weeks;
• seborrheic dermatitis 2 weeks.

Special instructions

Keep the cylinder upright when spraying.

Form of production

Spray for external use

Storage conditions

At a temperature of 4-30 °C

Shelf life

2 years

Active ingredient

Pyrithione zinc

Dosage form

spray for external use

Description

Pregnant women as prescribed by a doctor, Nursing mothers as prescribed by a doctor, For adults, Children over 1 year of age

Indications

Dermatitis, Eczema, Neurodermatitis, Psoriasis, Allergies