Composition
of 5 ml: – loratadine 5 mg
Auxiliary substances:
citric acid,
succinic acid,
propylene glycol,
glycerol,
nipagin,
nipazole,
aspartame (1.5 mg / ml),
sorbitol,
flavoring agent,
water.
Pharmacological action
CLARISENS SYRUP is a long-acting H1-histamine receptor blocker.
Inhibits the release of histamine and leukotriene C4 from mast cells.
Prevents the development and eases the course of allergic reactions.
It has anti-allergic, antipruritic, and antiexudative effects.
Reduces capillary permeability, prevents the development of tissue edema, and relieves smooth muscle spasms.
Indications
Allergic rhinitis (seasonal and year-round), conjunctivitis, pollinosis, urticaria (including chronic idiopathic), angioedema, itchy dermatosis; pseudoallergic reactions caused by histamine release; allergic reactions to insect bites.
Contraindications
Hypersensitivity, lactation period.
With caution.
Liver failure, pregnancy.
Interaction
CYP3A4 inhibitors (including ketoconazole, erythromycin), CYP3A4 and CYP2D6 inhibitors (cimetidine, etc. ) increase the concentration of loratadine in the blood.
Inducers of microsomal oxidation (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) reduce the effectiveness.
How to take, course of use and dosage
Adults and children with a body weight of more than 30 kg – 10 mg 1 time a day.
In case of hepatic insufficiency, the initial dose is 5 mg / day.
Children from 2 to 12 years of age with a body weight of less than 30 kg – 5 mg / day in 1 reception.
Special instructions
During the treatment period, care should be taken when driving vehicles and doing other activities. potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Form of production
Syrup.
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25 °C
Shelf life
2 years
Active ingredient
Loratadine
Dosage form
solution for oral use
Description
Children over 2 years old
Indications
Allergy, Eczema, Dermatosis, Conjunctivitis, Runny Nose, Allergic Rhinitis, Pollinosis, Insect Bites, Dermatitis, Angioedema, Urticaria, Allergic Conjunctivitis
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Side effects of Clarisense, 1mg/ml syrup, 100ml
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