Clenzit-S, gel, 30g

Composition

Active ingredients:

Adapalene (micronized) 1 mg;

Clindamycin (as phosphate) 10 mg.

Auxiliary substances:

Disodium edetate;

Carbomer 940 (carbopol 940);

Propylene Glycol;

Methylparahydroxybenzoate;

Phenoxyethanol;

Poloxamer 407;

Sodium hydroxide;

Purified water.

Pharmacological action

Clenzit C gel is a combination drug for the treatment of acne (acne), topical application. The active ingredients are Adapalene and Clindamycin.

Adapalene, a retinoid derivative, exhibits anti-inflammatory and comedonolytic activity. It has an effect on open and closed comedones, helps to normalize the processes of epidermal differentiation and keratinization.

The drug reduces the binding time of follicular epithelial cells, which contribute to the formation of microcomedones, and also inhibits chemokinetic reactions and chemotaxis of polynuclear cells.

The antimicrobial agent Clindamycin belongs to the lincosamide group and has bacteriostatic activity against many microorganisms. Clindamycin binds to the 50S subunit of ribosomal membranes and inhibits protein replication in the bacterial cell.

It also has a bactericidal effect against some gram-positive cocci.

When therapy is carried out with the use of Clenzit C, in patients with acne, there is a decrease in the intensity of inflammation, a decrease in acne elements, as well as a decrease in the number of comedones and an overall improvement in the condition of the skin of the face.

Due to the external use of Clenzit C, its systemic absorption is insignificant.

Indications

Treatment of acne (acne).

Contraindications

• hypersensitivity to Adapalene, Clindamycin and other ingredients of the drug;
• lactation period;
• pregnancy period.

Use with caution for eczema and dermatitis.

How to take, course of use and dosage

Externally, before applying the gel, it is necessary to clean and dry the skin.

With a light touch, apply the gel evenly to the affected surface 1 time a day before going to bed, avoiding getting the gel in the eyes and on the lips and other mucous membranes.

The course of treatment is from 2 to 4 weeks.

Repeat the course of treatment — after consultation with your doctor.

Special instructions

In the initial stages of treatment, there may be an exacerbation of acne, which disappears during treatment.

In case of skin irritation, stop using the gel (temporarily or permanently). Avoid exposure to the sun and the use of artificial UV radiation (tanning beds).

If prolonged exposure to the sun is necessary, do not apply the gel the day before and the day after sun exposure.

Do not use cosmetics with a drying or irritating effect at the same time (for example, cologne or ethanol-containing products). It is not allowed to use the gel for the treatment of damaged skin and burns.

Form of production

Gel for external use.

Storage conditions

In a dark place, at a temperature not exceeding 25 °C (do not freeze)

Shelf life

2 years

Active ingredient

Adapalene, Clindamycin

Dosage form

gel for external use

Indications

Acne