ATC code | M05BA03 |
---|---|
CAS Number | 51310-79-6 |
Other product names | Clodronate, Clodronate sodium, Clodronic acid |
Dosage form | Capsules |
Active ingredient | Clodronate sodium |
Other ingredients | Lactose monohydrate, pregelatinised starch, magnesium stearate, colloidal anhydrous silica, hypromellose, titanium dioxide (E171), iron oxide yellow (E172), iron oxide red (E172), sodium laurilsulfate, purified water |
Pharmacological classification | Bisphosphonate |
Pharmacological action | Inhibits bone resorption, reduces osteoclast activity, prevents bone loss |
Storage conditions | Store below 25°C |
Clobir Capsules 400 mg: A Comprehensive Guide
Clodronate is the active component in the 400 mg Clobir capsule medicine. This is a bisphosphonate, a kind of medication meant to stop bone resorption—that is, the process by which old bone breaks down. Conditions including Pagets disease of bone, osteoporosis, and hypercalcemia involving too high bone resorption are treated using Clobir Capsules 400 mg.
Ingredients in Clobir Capsules 400mg
There is 400 mg of clodronate in every Clobir capsule. To enable the capsules to be stable and easy to swallow, they could also contain other inactive components, including fillers, binders, and disintegrants.
How Clobir Capsules 400 mg Work and Their Benefits
Working by reducing the activity of osteoclasts, the cells in charge of breaking down bone, Clobir Capsules 400 mg This slows down the pace of bone resorption, therefore strengthening bones and preventing fractures. Effective in treating a range of disorders, Clobir capsules (400 mg) have been shown to:
- Bone Pagets disease:
- Porsonosis
- Hypercalciemia
Uses of Clobir Capsules 400 mg
Many disorders, including increased bone resorption, are treated with Clobir capsules (400 mg); these include:
- Pagets disease of bone: This disorder causes bones to grow unusually big and weak. Clobir Capsules 400 mg can help to slow down the course of the disease and lessen bone pain.
- Osteoporosis: The disorder known as osteoporosis weakens bones and increases their fracture risk. Clobir Capsules 400 mg can assist in lowering the risk of fractures and boosting bone density.
- Hypercalcemia: Hypercalcemia is the disorder marked by overly high blood calcium levels. One can help to reduce blood calcium levels by using Clobir Capsules 400 mg.
One should take Clobir Capsules 400 mg exactly as advised by their doctor. Usually one capsule is given once a day; your doctor may change the dosage depending on your particular requirement. To obtain the most from the medicine, one should routinely take Clobir Capsules 400 mg. Stopping Clobir Capsules 400 mg without consulting your doctor will raise your chance of fractures.
Dosage and Administration of Clobir Capsules 400 mg
The ailment being treated as well as the individual patient will affect the Clobir Capsule 400 mg dosage. You should really pay close attention to what your doctor orders. Never take more or less than advised by your doctor; also, never take the drug for longer than advised.
Potential Side Effects of Clobir Capsules 400 mg
Clobir Capsules 400 mg can have negative effects, just like every drug. Not everyone using Clobir Capsules 400 mg, though, will have negative effects. Common side effects of Clobir Capsules 400 mg consist in:
- Nausea
- Pertussiveness
- The diarrhea
- Abdominal discomfort
- Pain in the head
- Muscle pain
Though rare, more major side effects do happen. These include:
- Esophagitis, or oesophageal inflammation,
- Osteonecrosis of the jaw, or death of bone in the jaw,
- Normal femoral fractures
Should you have any side effects—especially severe ones—you should get right back to your doctor.
Contraindications for Clobir Capsules 400 mg
Not everyone would fit Clobir Capsules 400 mg. If you: do not use Clobir Capsules 400 mg if you:
- Either allergic to clodronate or another component in Clobir Capsules 400mg
- Your blood has low calcium content.
- Having renal issues
- You are nursing or pregnant.
Before you begin using Clobir Capsules 400mg, be sure your doctor knows about all of your medical issues, including any allergies.
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