Corvalol Fito pills 1.16mg + 28mg + 16.4mg, 50pcs

Composition

Per tablet:

Active ingredients:

motherwort herb extract (motherwort dry extract) – 28.00 mg,

ethylbromisovalerianate (ethyl ether of alpha-bromisovaleric acid) -16.40 mg,

peppermint leaf oil (peppermint oil) – 1.16 mg.

Auxiliary substances:

lactose (lactose monohydrate) – 158.42 mg,

betadex (beta-cyclodextrin) – 111.10 mg,

potato starch-71.12 mg,

magnesium aluminometasilicate (Neusiline UFL 2) – 8.00 mg,

talc – 4.00 mg,

magnesium stearate-1.80 mg

Pharmacological action

Sedative

Pharmacodynamics

A combined drug whose action is determined by the properties of its constituent substances. It has a sedative and antispasmodic effect, moderate cardiotonic effect (slows down the rhythm and increases the strength of heart contractions), has moderate hypotensive properties.

Ethylbromizovalerianate has a sedative and antispasmodic effect due to irritation, mainly of the oral and nasopharyngeal receptors, a decrease in reflex excitability in the central nervous system and increased inhibition in cortical neurons and subcortical structures of the brain, as well as a decrease in the activity of central vasomotor centers and a direct local antispasmodic effect on smooth muscles.

Motherwort herb has a pronounced sedative (calming), moderate cardiotonic (slows down the rhythm and increases the strength of heart contractions) effect, moderate hypotensive effect.

Peppermint oil has a reflex vasodilating, antispasmodic, mild choleretic, antiseptic effect. The mechanism of action is associated with the ability to irritate the “cold” receptors of the oral mucosa and reflexively expand mainly the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the mucous membrane receptors of the gastrointestinal tract (GIT), increasing intestinal motility.

Pharmacokinetics

Data on the pharmacokinetics of ethylbromisovalerianate, motherwort, and peppermint components are not available.

Indications

As a symptomatic (sedative and vasodilator) agent for functional disorders of the cardiovascular system. Neurosis-like states, accompanied by increased irritability, with a violation of falling asleep, tachycardia, a state of agitation with pronounced vegetative manifestations. As an antispasmodic agent – for intestinal spasms.

Use during pregnancy and lactation

The safety of using the drug Corvalol Phyto, tablets during pregnancy has not been established, the use of the drug during pregnancy is contraindicated. There are no data on the penetration of the components of the drug into breast milk, so if it is necessary to use the drug during lactation, the question of stopping breastfeeding should be decided.

Contraindications

– Hypersensitivity to the components of the drug;

– severe renal and / or liver dysfunction;

– pregnancy;

– lactation (breastfeeding);

– children under 18 years of age (efficacy and safety have not been established);

– lactose intolerance, lactase deficiency, glucose-galactose malabsorption.

If you have one of these diseases/If you have any serious medical conditions, be sure to consult your doctor before taking the drug.

Side effects

From the immune system:  allergic reactions.

From the central nervous system:  drowsiness, weakness, dizziness, decreased ability to concentrate;

From the gastrointestinal tract: dyspepsia.

These symptoms disappear with a decrease in the dose of the drug or discontinuation of the drug.

With prolonged use of high doses of the drug, drug dependence may develop, as well as bromine accumulation in the body and the development of bromism, the manifestations of which are: depressive mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements, drug dependence.

If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

With the simultaneous use of the drug Corvalol Phyto, tablets with drugs that inhibit the activity of the central nervous system (sedatives, sleeping pills, antipsychotics, tranquilizers), mutual strengthening of the effects is possible.

Enhances the effect of antispasmodic, analgesic agents.

Alcohol increases the effect of the drug and its toxicity.

How to take, course of use and dosage

For oral use, before meals, with water.

For tablets,0.58 mg + 14.00 mg + 8.20 mg: adults take 2 tablets 2 times a day.

For tablets,1.16 mg + 28.00 mg + 16.40 mg: adults: 1 tablet 2 times a day.

With tachycardia, it is possible to increase the single dose to 3 tablets. The maximum daily dose is 6 tablets.

The course of treatment is 4 weeks (28 days). The duration of admission may be extended on the recommendation of a doctor.

Overdose

Overdose is possible with frequent and prolonged use of the drug. If the recommended doses are exceeded, the dose-dependent side effects may increase.

Symptoms:  weakness, drowsiness, dizziness. With prolonged use, chronic bromine intoxication may occur (see section Side effects).

Treatment:  symptomatic.

Description

Round, flat-cylindrical tablets of light brown color with inclusions of lighter and darker color, with a chamfer and risk, with a weak characteristic smell.

Special instructions

There is no experience of using the drug in children under 18 years of age, during pregnancy and during breastfeeding.

Long-term use of the drug in high doses is not recommended, due to the possible toxic effect of bromine accumulation in the body.

During the use of the drug, do not drink alcohol.

Storage conditions

At a temperature not exceeding 25 ° C. Keep out of reach of children.

Active ingredient

Peppermint Leaf Oil, Motherwort Herb Extract, Ethylbromisovalerianate

Dosage form

Tablets