Composition
>of 1 g of cream contains: Active ingredient: Dexpanthenol 50 mg; Excipients: Propylene glycol 100 mg,0.8 mg methyl parahydroxybenzoate, Parahydroxybenzoate 0.2 mg, Macrogol cetostearyl 16 mg, Cetostearyl alcohol [cetyl alcohol 60%, stearyl alcohol, at least 40%] 40 mg, Paraffin liquid 80 mg, Vaseline 100 mg, Sodium hydrogen phosphate, dodecahydrate 0.2 mg, Potassium dihydrogen 7,8 mg, purified Water to 1 g.
Pharmacological action
Dexpanthenol is a derivative of pantothenic acid.
Dexpanthenol is converted in the body to pantothenic acid, which is a component of coenzyme A and is involved in the processes of acetylation, in the synthesis of acetylcholine, corticosteroids, porphyrins.
In addition, it takes part in almost all metabolic processes (the tricarboxylic acid cycle, the exchange of carbohydrates, fats and fatty acids, phospholipids, proteins, etc. ), stimulates the regeneration of the skin and mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers.
It has regenerating, metabolic and weak anti-inflammatory effects.
When applied externally, it is rapidly absorbed by the skin and converted to pantothenic acid, binds to plasma proteins (mainly beta-globulin and albumin).
Its concentration in the blood is 0.5-1 mg/l, in the blood serum-100 mcg/l. Pantothenic acid is not metabolized in the body (except for inclusion in Co-A), it is excreted unchanged.
Indications
- In case of violation of the integrity of the skin: healing of burns (including sunburn), minor skin injuries (abrasions, cuts, cracks, etc. ).
- Prevention and treatment of dry skin, including as a consequence of dermatitis of various origins (manifested by peeling, redness, irritation, tightness), as well as daily care of areas of the skin that are most affected by external factors (face, hands), including due to weathering.
- For the care of the breast during lactation (cracks and redness of the nipples of the breast), for the care of children and children (diaper rash, ” diaper ” dermatitis).
Contraindications
Hypersensitivity to the components of the drug.
Side effects
Allergic reactions. Allergic skin reactions (for example, contact dermatitis, allergic dermatitis, itching, redness, eczema, rash, hives, skin irritation). If any of the side effects listed in the instructions get worse, or any other side effects that are not listed in the instructions are noted, you should immediately inform your doctor.
Interaction
Interactions with other drugs are unknown.
How to take, course of use and dosage
Externally. The cream is applied in a thin layer 1-2 times a day on pre-cleansed, dry skin and lightly rubbed.
When caring for the mammary gland, the cream is applied to the surface of the nipples after each feeding.
When caring for infants, the cream is applied with each change of diapers (diapers, diapers).
Overdose
Overdose cases are unknown.
Special instructions
For external use only. Do not apply to wet wounds.
Influence on the ability to drive vehicles and mechanisms
The drug does not affect the ability to drive vehicles or engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Form of production
Cream for external use
Storage conditions
At a temperature not exceeding 25 °C.
Keep out of reach of children.
Shelf
life is 2 years.
Active ingredient
Dexpanthenol
Dosage form
cream
Description
For children, Pregnant women, Nursing mothers, And adults
Indications
Wounds, Sunburn, Trophic Ulcers, Burns, Bedsores, Cracked Nipples in Nursing Mothers, Minor Skin Injuries, Diaper Rash, Dermatitis, Healing
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Side effects of D-Panthenol-Nizhpharm external cream 5%, 50g.
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