D-Panthenol Novathenol ointment for external use, 50g

Composition

100 g of ointment contains:

Active ingredient:

dexpanthenol 5,00 g;

excipients:

vaseline 27.00 g;

paraffin liquid 10.00 g;

lanolin 17.00 g;

cholesterol 0.50 g;

isopropyl myristate 3.00 g;

methyl parahydroxybenzoate 0.07 g;

propyl parahydroxybenzoate 0.03 g;

water 37.40 g.

Pharmacological action

Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid, a water-soluble B vitamin (vitamin B5), is a component of coenzyme A (Co-A). It stimulates skin regeneration, normalizes cellular metabolism, and increases the strength of collagen fibers.

An increase in the need for pantothenic acid is observed when the skin or tissues are damaged, and its deficiency can be compensated by external use of dexpanthenol. Its optimal molecular weight, hydrophilicity and low polarity make it possible for it to penetrate all layers of the skin. It has a weak anti-inflammatory effect.

Pharmacokinetics:

When applied topically, it is rapidly absorbed and converted to pantothenic acid, binds to plasma proteins (mainly beta-globulin and albumin).

Its concentration in the blood is 0.5-1 mg/l, in the blood serum-100 mcg/l. Pantothenic acid is not metabolized (except for inclusion in Co-A), and is excreted unchanged by the kidneys.

Indications

Skin integrity disorders caused by mechanical, chemical, temperature factors or after surgical interventions:

the various burns (including solar);

– scratches, abrasions, wounds, bedsores;

– poorly healing skin grafts, aseptic surgical wounds;

– inflammatory processes on the skin: dermatitis, boils, ulcers of the lower extremities;

the care of the skin around tracheostomy, gastrostomy and colostomy;

– treatment and prevention of consequences of adverse effects on the skin of environmental factors (cold, wind, moisture).

For children:  diaper dermatitis, skin irritation, treatment and prevention of diaper rash. Cracked and inflamed nipples of the breast in nursing mothers.

It is also used to treat and protect dry skin, as a source of neutral fats and dexpanthenol.

Contraindications

D-Panthenol ointment should not be used for hypersensitivity to the components of the drug.

Side effects

Allergic reactions (including delayed ones due to the presence of parahydroxybenzoates in the preparation).

If any of the side effects listed in the instructions get worse or you notice any other side effects not listed in the instructions, tell your doctor.

How to take, course of use and dosage

Externally.

The ointment is applied 2-4 times a day (if necessary more often), a thin layer on the affected area of the skin, lightly rubbing. If applied to an infected skin surface, it should be pre-treated with any antiseptic.

Nursing mothers should lubricate the surface of the nipple with ointment after each breast-feeding.

For children (including newborns), the ointment is applied after each change of underwear or water procedure.

The duration of use of the drug and the possibility of repeating the course of treatment depend on the individual characteristics of the course of the disease in the patient, and is determined by the achieved therapeutic effect and tolerability of the drug.

Special instructions

Treatment of trophic ulcers and poorly healing skin grafts should be carried out under the supervision of the attending physician.

Do not apply to wet wounds.

Storage conditions

Keep out of the reach of children in a dark place, at a temperature not exceeding 25 °C.

Shelf

life is 2 years.

Do not use after the expiration date.

Active ingredient

Dexpanthenol

Dosage form

ointment

Description

Nursing Mothers, For adults, For pregnant women, For children

Indications

Trophic Ulcers, Healing, Bedsores, Wounds, Sunburn, Dermatitis, Minor Skin Injuries, Cracked Nipples in Nursing Mothers, Diaper Rash, Burns