Dolgit cream 5%, 50g

Composition

100 g of cream contains 5 g of the Active ingredient ibuprofen; excipients: medium-chain triglycerides, purified water, glyceryl monostearate, propylene glycol, macrogol-100-stearate, macrogol-30-stearate, xanthan gum (Keltrol F), sodium methyl parahydroxybenzoate, lavender oil, orange blossom oil (nerol oil).

Pharmacological action

The drug has a local analgesic, anti-inflammatory and decongestant effect. Suppresses the production of inflammatory mediators. It selectively blocks cyclooxygenase (COX-1 and COX-2) and has an inhibitory effect on the synthesis of prostaglandin E2 (PGE2), prostacyclin (PGI2) and thromboxane B2 (TB2).

The analgesic effect is most pronounced in inflammatory pain. Causes a decrease or disappearance of pain, including pain at rest and during movement; reduces morning stiffness and swelling of the joints. Helps to increase the volume of movement. In addition to the anti-inflammatory effect, ibuprofen reduces platelet aggregation at the site of inflammation, as well as white blood cell migration and the release of lysosomal enzymes in the area of inflammation.

When the cream is applied to the skin, ibuprofen penetrates deeper tissues (subcutaneous tissue, muscles, joints, synovial fluid) and reaches therapeutic concentrations in them.

The therapeutic effect in the application area is achieved by direct distribution through the skin into the target tissue. In a small amount is determined in the blood plasma. With the recommended method of application, the concentration in the synovial fluid is about 2 micrograms/ml.

Indications

• Inflammatory and degenerative diseases of the musculoskeletal system:
• Arthritis (rheumatoid, psoriatic).
• Joint syndrome in rheumatism and gout exacerbation.
• Shoulder-scapular periarthritis.
• Ankylosing spondylitis (ankylosing spondylitis).
• Deforming osteoarthritis.
• Osteochondrosis with radicular syndrome.
• Sciatica.
• Sciatica.
• Myalgia (rheumatic and non-rheumatic origin).
• Lumbago.
• Tendivitis, tendovaginitis, bursitis.
• Injuries (sports, industrial, domestic) without violating the integrity of soft tissues (including dislocations, sprains, muscle or ligament tears, bruises, post-traumatic soft tissue edema).

Contraindications

Hypersensitivity to ibuprofen, components of the drug and other NSAIDs, wet dermatoses, eczema, skin integrity disorders (including infected abrasions and wounds) at the site of application of the cream; pregnancy, lactation; children under 14 years of age.

Side effects

The drug is usually well tolerated. In rare cases, there may be temporary signs of local skin irritation in the form of redness, swelling, rashes, itchy skin, burning and tingling sensations. In case of hypersensitivity to NSAIDs, bronchospasm may occur. With prolonged use of the drug in particularly sensitive patients, systemic side effects may develop.

Interaction

You should consult your doctor before using Dolgit cream, if other medications are used.

When ibuprofen was used externally, no interactions with other drugs were detected.

How to take, course of use and dosage

The drug should be applied topically.

A strip of cream 5-10 cm long is applied to the skin in the area of the painful area and thoroughly rubbed with light movements until the drug is completely absorbed 2-3 times a day. The course of treatment should not exceed 10 days without consulting a doctor.

The duration of therapy with Dolgit depends on the severity of the disease and the nature of the damage.

Overdose

Cases of overdose with Dolgit cream are not described.

Symptoms:  if the drug is accidentally ingested, nausea and vomiting may occur.

Treatment:  you should clear your stomach (induce vomiting, take activated charcoal) and consult a doctor. Further treatment, if necessary, is symptomatic.

Special instructions

The drug should not be applied to the open wound surface, damaged skin or mucous membranes (avoid contact with eyes).

If the therapy is ineffective, you should consult a doctor.

In severe cases, it is recommended to combine local therapy with oral NSAIDs.

– Use in pediatrics Dolgit in the form of cream should not be used in children under the age of 12 years without consulting a doctor.

– Influence on the ability to drive vehicles and manage mechanisms The use of Dolgit cream does not affect activities that require increased attention, coordination of movements, high speed of mental and physical reactions (including transport drivers, car maintenance personnel).

Form of production

Cream for external use 5% in aluminum tubes of 20 g,50 g and 100 g, sealed with a membrane and a screw-on plastic cap. One tube together with the instructions for use in a cardboard box.

Storage conditions

Store in a dry place at a temperature of 15° to 25°C. Keep out of reach of children. Do not use after the expiration date.

Shelf

life is 3 years.

Active ingredient

Ibuprofen

Dosage form

cream