Composition
Film-coated tablets orange color, round, biconvex.
1 tab. naphthidrofuryl oxalate 50 mg
Excipients:
lactose monohydrate,
microcrystalline cellulose,
wheat starch,
copovidone,
colloidal silicon dioxide,
magnesium stearate,
talc.
Shell composition:
titanium dioxide, talc, magnesium stearate, macrogol 6000, methacrylic acid and ethyl acrylate copolymer, dye sunset yellow (E 110).
Pharmacological action
 A drug that improves brain and peripheral blood circulation
Indications
recovery period after cerebral circulatory disorders; peripheral circulatory disorders (intermittent claudication, Raynaud’s disease, trophic ulcers).
Contraindications
individual hypersensitivity to the drug;myocardial infarction (acute phase);hypotension;hemorrhagic stroke (acute phase);epilepsy, increased convulsive readiness;chronic heart failure II–III stage (III–IV NYHA functional classification of heart failure new York heart Association);tachyarrhythmia;age to 18 years (efficacy and safety not established). With caution: angle-closure glaucoma;prostatic hyperplasia.
Side effects
When taken orally in doses from 300 to 600 mg, Dusofarm is generally well tolerated. Possible side effects: nausea, vomiting, epigastric pain, intestinal colic, diarrhea, decreased appetite, headache, dizziness, sleep disturbance, reversible increase in liver enzyme activity, ulcers of the gastric mucosa, allergic reactions.
Interaction
Increases the antihypertensive effect of antihypertensive drugs.
In this regard, more frequent monitoring of blood pressure is recommended — at the beginning of combined treatment with Dusopharm and antihypertensive agents.
How to take, course of use and dosage
Inside, whole, without chewing, with a sufficient amount of liquid, (it is recommended to drink water). For disorders of cerebral circulation: in a daily dose of 300 mg (2 tablets 3 times a day). In case of peripheral circulatory disorders: in a daily dose of 500-600 mg (in 3 divided doses). Duzopharm is recommended for long-term oral therapy (up to 6 months). No dose adjustment is required in patients with renal/hepatic insufficiency.
Overdose
Symptoms: increased severity of side effects, ventricular arrhythmia, anxiety, decreased blood pressure, bradycardia. Treatment: gastric lavage, use of activated charcoal and laxatives, symptomatic treatment. There is no specific antidote.
Special instructions
Duzopharm does not adversely affect psychomotor reactions and the ability to drive a car. At the beginning of treatment, it is recommended to monitor the individual tolerability of the drug and monitor the possible hypotensive effect in the respective patients. The drug contains lactose monohydrate, so it is not recommended to use it for people suffering from lactase deficiency, galactosemia or glucose-galactose malabsorption syndrome. Patients with celiac disease (gluten enteropathy) should consider that the tablet contains wheat starch.
Active ingredient
Naftidrofuryl
Conditions of release from pharmacies
By prescription
Dosage form
Tablets
Description
For adults
Indications
Raynaud’s disease, Trophic Ulcers, Cerebrovascular accident
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Side effects of Dusopharm, pills 50mg, 60pcs.
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