Composition
Per 1 capsule:
Active ingredient:  nifuroxazide – 200.0 mg. Auxiliary substances:  sucrose-70.0 mg; microcrystalline cellulose-41.5 mg; corn starch-35.0 mg; magnesium stearate-3.5 mg. Capsule body composition:  quinoline yellow dye – 0.7500%; sunset yellow dye-0.0059%; titanium dioxide-2.0000%; gelatin-up to 100%. Capsule cap composition:  quinoline yellow dye – 0.7500%; sunset yellow dye-0.0059%; titanium dioxide-2.0000%; gelatin-up to 100%.
Pharmacological action
Nifuroxazide-is a derivative of nitrofuran, has an antimicrobial effect. Highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp. ; Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolytique, Staphylococcus spp. Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae, Proteus indologenes. Resistant to nifuroxazide: Klebsiella spp., Proteus mirabilis, Providencia spp., Pseudomonas spp. Presumably, it blocks the activity of dehydrogenases and inhibits respiratory chains, the tricarboxylic acid cycle, and a number of other biochemical processes in the microbial cell. It does not disturb the balance of intestinal microflora. In acute bacterial diarrhea, it restores intestinal eubiosis. When infected with enterotropic viruses, it prevents the development of bacterial superinfection.
Pharmacokineticsafter oral use, nifuroxazide is practically not absorbed from the gastrointestinal tract and has no systemic effect; 99% of the dose taken remains in the intestine and exerts its antimicrobial effect there. Nifuroxazide is excreted by the intestines: 20% unchanged, and the remaining amount of nifuroxazide is chemically modified.
Indications
Acute bacterial diarrhea that occurs without deterioration of the general condition, fever, intoxication.
Contraindications
- hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug;
- children under 3 years of age (for this dosage form);
- pregnancy;
- sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.
Side effects
Allergic reactions (skin rash, urticaria, angioedema, anaphylactic shock). If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.
Interaction
Concomitant use with drugs that cause the development of disulfiram-like reactions, drugs that inhibit the function of the central nervous system is not recommended. If you are taking other medications (including over-the-counter medications), please consult your doctor before using Elufor.
How to take, course of use and dosage
Inside. The capsule should be swallowed whole, washed down with a small amount of water. For adults: 1 capsule of 200 mg 4 times a day (the interval between doses is 6 hours). Children from 6 to 18 years: 1 capsule of 200 mg 3-4 times a day (the interval between doses is 6-8 hours). Children from 3 to 6 years: 1 capsule of 200 mg 3 times a day (the interval between doses is 8 hours). The duration of treatment is 5-7 days, but not more than 7 days. If there is no improvement during the first 3 days of taking it, then you should consult a doctor. Use the drug only according to the method of use and in the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.
Special instructions
When treating diarrhea simultaneously with nifuroxazide therapy, rehydration therapy should be performed. In case of bacterial diarrhea with signs of systemic damage (deterioration of the general condition, increased body temperature, symptoms of intoxication or infection), you should consult a doctor about the use of systemic antimicrobial drugs. A daily dose of 800 mg contains 0.023 XE. Alcohol consumption is prohibited during therapy with Elufor. If you experience symptoms of an allergic reaction (including shortness of breath, rash, itching), you should stop taking the drug and consult a doctor.
Influence on the ability to drive vehicles and mechanisms
The drug does not affect the ability to drive vehicles and mechanisms.
Storage conditions
At a temperature not exceeding 25 °C. Keep out of reach of children.
Shelf
life is 3 years. Do not use the product after the expiration date.
Active ingredient
Nifuroxazide
Dosage form
Capsules
Description
Children over 3 years old, For adults
Indications
Poisoning, Salmonellosis, Intestinal Infections, Diarrhea
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Side effects of Elufor capsules 200mg, 12pcs.
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