Endofalk solution for oral use, 55.318g sachets, 6pcs

Composition

1 sachet of powder contains (55.318 g):

active ingredients:

macrogol 3350 52.5 g,

sodium chloride 1.4 g,

sodium bicarbonate 0.715 g,

potassium chloride 0.185 g,

excipients:

colloidal silicon dioxide-0.00046 g;

fruit flavor-0.4 g;

orange flavor-0.1 g;

sodium saccharinate-0.018 g

Pharmacological action

Pharmacodynamics

The laxative effect of Endofalk is due to the action of the components included in the preparation and is manifested in the occurrence of diarrhea. Macrogol 3350 (polyethylene glycol), due to the creation of an isoosmolar solution, prevents absorption in the stomach and intestines and promotes accelerated passage and excretion of gastrointestinal contents.

Salt electrolytes, which are part of the preparation, prevent a violation of the water-salt balance of the body.

Pharmacokinetics

High molecular weight polyethylene glycols are not absorbed from the gastrointestinal tract and are not metabolized during passage (they prevent undesirable gas formation caused by the metabolizing action of bacteria).

Indications

Preparation for endoscopic or X-ray examination of the lower intestine;

Preparation for surgical procedures that require the absence of intestinal contents — chyme.

Use during pregnancy and lactation

There is still no experience of clinical use of Endofalk in pregnant women.

Therefore, Endofalk should be prescribed during pregnancy and lactation only for strict indications.

Contraindications

• severe violations of the patient’s general condition (dehydration, heart and / or renal failure);
• intestinal obstruction;
• toxic expansion of the colon;
• gastric stenosis;
• perforation of the stomach or intestines;
• erosive and ulcerative lesions of the gastrointestinal tract;
• severe colitis in the acute phase;
• violations of excretory function of the kidneys;
• children under 18 years of age.

Side effects

From the gastrointestinal tract: rarely-nausea, vomiting, flatulence, cramping pains; at the beginning and some time after taking-a feeling of heaviness and discomfort in the abdomen; sleep disorders; very rarely-allergic reactions.

From the central nervous system: very rarely-sleep disorders and general malaise.

Hypersensitivity reactions: very rare — allergic reactions.

If you find any of these effects, you should immediately consult your doctor.

Interaction

The process of releasing the intestinal contents caused by the action of the drug can lead to a violation of the absorption of other drugs taken simultaneously with it.

How to take, course of use and dosage

Endofalk is taken orally, for adults and children over 18 years of age, in the form of a solution.

The solution can be taken orally or administered through a nasogastric tube the night before or in the morning on the day of the intended bowel examination or surgery. In the evening before and in the morning on the day of the study, it is also necessary to refrain from eating.

To prepare 1 liter of solution, the contents of 2 sachets are dissolved in 1/2 liter of cooled boiled (purified) water, then the volume of the solution is adjusted to 1 liter. To completely cleanse the intestines, it is recommended to prepare and take at least 3 liters of Endofalk solution.

The time during which the solution is taken is 3-4 hours. The recommended dose is 3-4 liters of the solution, taken in portions of 200-300 ml every 10 minutes.

Special instructions

If you experience any side effects, you should consult your doctor.

It is not recommended for use in children.

Elderly patients with existing concomitant diseases are recommended to use the drug under medical supervision. The patient should inform the attending physician about all medications taken simultaneously with Endofalk.

Influence on the ability to drive vehicles and moving mechanisms. Not detected.

Form of production

Powder for preparation of an oral solution

Storage conditions

In a dark place, at a temperature not exceeding 25 °C. The prepared solution should be stored for no more than 3 hours at 25 °C or 48 hours at 5 °C (in the refrigerator). Keep out of reach of children

Shelf

life is 5 years.

Active ingredient

Macrogol, Sodium Chloride, Sodium Bicarbonate, Potassium Chloride

Dosage form

solution for oral use

Description

For adults

Indications

Preparation for ultrasound and X-ray of the abdominal cavity