ATC code | L01XC06 |
---|---|
CAS Number | 151834-92-4 |
Other product names | Cetuximab |
Dosage form | Solution for infusion |
Active ingredient | Cetuximab |
Other ingredients | Sodium chloride, glycine, polysorbate 80, citric acid monohydrate, sodium hydroxide and water for injections |
Pharmacological classification | Monoclonal antibody |
Pharmacological action | Binds to the epidermal growth factor receptor (EGFR), an antigen on the surface of certain cancer cells. EGFR activates proteins called RAS, Slows or stops the growth of cancer cells |
Storage conditions | Store in a refrigerator (2°C – 8°C). Do not freeze. |
Erbitux 5 mg/mL: A Targeted Cancer Treatment
Prescription medicine Erbitux 5 mg/mL treats some forms of cancer. Being a monoclonal antibody, this kind of protein is meant to target and cling to particular bodily structures. In this instance, Erbitux targets the surface-based epidermal growth factor receptor (EGFR), present on some cancer cells. Erbitux stunts the proliferation of these cancer cells by binding to EGFR.
Erbitux 5 mg/mL Composition
Erbitux 5 mg/mL solution is colorless, preservative-free, and sterile. One milliliter of solution contains five milligrams of cetuximab. A twenty-mL bottle has 100 milligrams of cetuximab. Sodium chloride, glycine, polysorbate 80, citric acid monohydrate, sodium hydroxide, and water for injections make up Erbitux 5 mg/mLs additional constituents.
Benefits and Effects of Erbitux 5 mg/mL
Erbitux 5 mg/mL can help cancers growth to be slowed down and tumors shrank. This can increase your longevity and raise your quality of life. Although Erbitux is not a cancer cure, some people find it to be a suitable course of treatment.
Erbitux 5 mg/mL: Indications for Use
Combining erbitux 5 mg/mL with encorafenib treats several forms of cancer, including EGFR-expressing head and neck cancer (HNSCC) with a BRAF V600E mutation and metastatic colorectal cancer (CRC) that is KRAS mutation-negative (wild-type).
Erbitux 5 mg/mL: Usage Guide
Usually given once a week as an intravenuous infusion, Erbitux 5 mg/mL is your particular health condition, and the kind of cancer you have will determine the amount and frequency of administration. Your doctor will decide on your optimal course of action.
Erbitux 5 mg/mL: Dosage and Administration
Usually 400 mg/m2 body surface area, the first dose of Erbitux is given over around two hours. Following doses could be 250 mg/m2 body surface area given over 60 minutes. Erbitux can be prescribed either as a single agent or in concert with other chemotherapy medications.
Side Effects of Erbitux 5 mg/mL
Erbitux 5 mg/mL has side effects, just like other drugs. Some typical side effects consist in:
- Scar
- In acne
- Dieserung
- Appause
- Wearyness
More severe side effects can arise, including:
- Reactions related to infusion
- Disease of Interstitial Lung:
- Cardiopulmonary silence
- Electrolyte anomalies
Talk to your doctor about any side symptoms you find occurring. They can guarantee you get the finest possible treatment and help you control adverse effects.
Contraindications and Precautions for Erbitux 5 mg/mL
Not fit for everyone is Erbitux 5 mg/mL. Use it only if you
- Have a history of serious infusion responses to cetuximab or any other component in the drug; are allergic to either.
- Exist some kind of cardiac disease.
Before beginning Erbitux 5 mg/mL medication, be sure your doctor is aware of all your medical problems and sensitivities. They can evaluate your particular circumstances and ascertain whether this drug is suitable for you.
Storage Conditions for Erbitux 5 mg/mL
Store Erbitux 5 mg/mL refrigerated between 2 and 8°C (36–46°F). Shield from minor light. Please do not freeze. After eight hours at room temperature or twelve hours if refrigerated, discard the unused amount.
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