Composition
1 tablet contains:
Active ingredient:
erinit 0.01 g
Pharmacological action
Erinite is a venous vasodilator, has an antianginal effect. It stimulates the formation of nitric oxide in the vascular wall, which is an endothelial relaxing factor. Erynit reduces preload (dilation of peripheral veins and reduction of blood flow to the right atrium) and afterload (OPSS) on the heart; reduces the need for myocardial oxygen.
It restores blood flow in small endocardial vessels, improves blood flow in epicardial coronary arteries, and increases exercise tolerance in patients with coronary artery disease and angina pectoris. Reduces pressure in the “small” circulatory system.
Compared to nitroglycerin, Erinite has a slower but longer effect (up to 10 hours). When taken orally, the effect begins in 30-45 minutes (with sublingual – in 15-20 minutes), duration – 4-5 hours.
Indications
Prevention of angina attacks.
Contraindications
- hypersensitivity to the drug and other organic nitrates;
- severe hypotension;
- collapse;
- shock;
- acute myocardial infarction, occurring with orthostatic hypotension;
- craniocerebral trauma;
- cerebrovascular disease (especially hemorrhagic stroke);
- angle-closure glaucoma;
- pregnancy;
- lactation;
- simultaneous use of inhibitors PDE;
- the age of 18 years (effectiveness and safety not established).
Side effects
- Allergic reactions,
- headache,
- tinnitus,
- dizziness,
- nausea,
- weakness,
- tachycardia,
- increased fatigue,
- anxiety,
- increased sweating,
- decreased blood pressure,
- orthostatic hypotension;
- sometimes there is a disorder of intestinal function (diarrhea).
Interaction
If you are taking other medications at the same time, you should consult your doctor.
Under the influence of dihydroergotamine, the antianginal effect of Erynit may decrease. The combination of these drugs is considered irrational.
The combination with propranolol is rational, because the antianginal effect of Erynit is enhanced.
Ethanol enhances the effect of Erinite.
How to take, course of use and dosage
Inside (1 hour before meals),10-20 mg (1-2 tablets) 3-4 times a day, if necessary-up to 40 mg 4 times a day,80 mg 2 times a day is acceptable.
To prevent nocturnal attacks of angina pectoris,20 mg is prescribed before bedtime. The course of treatment usually lasts 2-4 weeks. Repeat courses — as prescribed by a doctor.
Special instructions
For the relief of angina attacks, the drug is of little use due to the slow onset of the effect.
It is necessary to exclude the use of ethanol during treatment.
With prolonged use, the therapeutic effect may decrease (due to the development of tolerance).
When using the drug once a day in combination with other antianginal agents, the risk of developing tolerance decreases.
Form of production
Tablets
Storage conditions
In a dark place, at a temperature not exceeding 25 °C
Shelf life
3 years
Active ingredient
Pentaerythrityl tetranitrate
Conditions of release from pharmacies
By prescription
Dosage form
Tablets
Description
For adults as directed by your doctor
Indications
Angina
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