Essentiale N solution 250mg/5ml 5ml ampoules, 5pcs

Composition

5 ml of the solution contains: Active ingredient: phosphatidylcholine from dried soybeans, containing 93% (3-sn-phosphatidyl) choline: synonyms – “essential phospholipids”, “EPL®” – 250 mg. Other ingredients: benzyl alcohol-45 mg, deoxycholic acid -115 mg, sodium chloride-12 mg, sodium hydroxide-11.5 mg, riboflavin-0.5 mg, alpha-tocopherol-0.75 mg, ethanol-16.304 mg, water for injection-4543.680 mg

Pharmacological action

The drug provides the liver, whose metabolic activity is impaired, with a high dose of ready-to-digest, high-energy “essential phospholipids”. These “essential phospholipids” are ideally combined with natural endogenous phospholipids in chemical structure. They mainly penetrate the liver cells, embedding themselves in their membranes.

“Essential phospholipids”:

• normalize liver function and enzyme activity of liver cells;
• reduce the level of energy consumption of the liver;
• promote the regeneration of liver cells;
• convert neutral fats and cholesterol into forms that facilitate their metabolism;
• stabilize the physical and chemical properties of bile.

Indications

Fatty liver degeneration (including diabetes mellitus); acute and chronic hepatitis, cirrhosis of the liver, necrosis of liver cells, hepatic coma and precoma, toxic liver damage; toxicosis of pregnancy; pre-and postoperative treatment, especially during operations in the hepatobiliary zone; psoriasis; radiation syndrome.

Contraindications

Hypersensitivity to any of the ingredients of Essentiale H; children under 3 years of age.

Caution: pregnancy, due to the presence of benzyl alcohol in the composition of the drug, which can penetrate the placental barrier (the use of drugs containing benzyl alcohol in premature newborns or premature newborns has been associated with the development of dyspnea syndrome with a fatal outcome).

Side effects

From the immune system: rarely-due to the content of benzyl alcohol in the preparation, hypersensitivity reactions may develop;

very rarely-allergic skin reactions (rash, exanthema or urticaria) are possible;

unknown frequency-pruritus.

How to take, course of use and dosage

The drug is intended for intravenous use, it should not be administered intramuscularly due to possible local irritation reactions. In the absence of other recommendations of the doctor-1-2 ampoules (5-10 ml) or in severe cases — 2-4 ampoules (10-20 ml) per day. The contents of 2 ampoules can be administered simultaneously. Do not mix in the same syringe with other drugs. It is recommended to dilute the solution with the patient’s blood in a ratio of 1: 1.

If it is necessary to dilute the drug, only 5 or 10% dextrose solution is used for infusion, and the solution of the diluted drug should remain transparent during the entire time of use.

Do not dilute the drug with electrolyte solutions (isotonic solution, Ringer’s solution)!

It is recommended to supplement parenteral use with oral use of the drug as soon as possible.

Special instructions

Only use a clear solution!

Form of production

Solution for intravenous use

Storage conditions

At a temperature of 2-8 °C

Shelf life

3 years

Active ingredient

Phospholipids

Conditions of release from pharmacies

By prescription

Dosage form

solution for infusions

Description

Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor, Adults as prescribed by a doctor

Indications

Pregnancy toxicosis, Psoriasis, Cirrhosis of the liver, Liver damage, Obesity, Cholelithiasis, Poisoning, Hepatitis, Atherosclerosis, After a course of antibiotic therapy, Alcoholism