ATC code | B03XA03 |
---|---|
CAS Number | 1385320-01-5 |
Other product names | Roxadustat |
Dosage form | Film-coated tablets |
Active ingredient | Roxadustat |
Other ingredients | Lactose, traces of soya lecithin and Allura Red AC aluminium lake (E129) |
Pharmacological classification | Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor |
Pharmacological action | Stimulates erythropoiesis, increases red blood cell production, reduces the need for erythropoietin |
Storage conditions | Store below 30°C |
Evrenzo 20mg: Treatment for Anemia in Chronic Kidney Disease
Designed to treat anemia related to chronic kidney disease (CKD) in adults, Evrenzo, which has the active component roxadustat, Being a first-in-class HIF prolyl-hydroxylase inhibitor, it acts by simulating the bodys natural reaction to low oxygen levels. This sets off the synthesis of erythropoietin, a hormone that increases red blood cell development. The higher red blood cell count helps your body receive more oxygen, therefore countering the weakness and tiredness sometimes linked with anemia.
What is Evrenzo 20mg Made Of?
The active ingredient of every Evrenzo 20 mg film-coated tablet is 20 mg of roxadustat. Additionally included in the tablets are several excipients, inactive components used in tablet formulation. The product information sheet that comes with the medicine offers a comprehensive list of the ingredients.
Benefits and Results of Evrenzo 20mg
For those with anemia associated with chronic renal disease, Evrenzo 20 mg provides a number of advantages. Here are several important consequences:
- Boosts Hemoglobin Levels: Evrenzo increases hemoglobin levels—the protein in charge of transporting oxygen in the blood—by increasing erythropoietin synthesis. Better oxygen transport all across the body follows from this.
- Helps to lower anemia symptoms. Anemia symptoms, including weakness, shortness of breath, and tiredness, should lessen as hemoglobin levels increase. You probably will have a better general quality of life and be more active.
- Might cut iron transfusions: By helping to increase iron availability, Evrenzo may help to lower the demand for iron transfusions. This is a major benefit since iron injections involve some hazards and can be uncomfortable.
What is Evrenzo Used For?
Specifically recommended for treating adult patients with severe anemia linked to chronic kidney disease (CKD), Evrenzo 20 mg is This is thus used to control anemia brought on by kidney illness. Though it targets the anemia symptom, Evrenzo is not a treatment for renal disease.
How to Use Evrenzo 20mg
Evrenzo should be taken orally three times a week, with a minimum of one day between each dosage. Your doctor will decide the particular dosage and frequency depending on your medical history and personal needs. You should pay great attention to your doctors directions.
Evrenzo 20mg: Dosage and Administration
Individualized dosage of Evrenzo 20 mg will help to reach and sustain target hemoglobin levels of 10 to 12 g/dL. Regular hemoglobin level monitoring by your doctor will help to modify your dosage as necessary. The highest dosage never exceeds 3.0 mg/kg body weight.
Possible Side Effects of Evrenzo 20mg
Though not everyone has adverse effects, Evrenzo 20 mg might cause them like all drugs. Typical adverse effects are:
- Higher potassium values
- Rising blood pressure
- Pregnancy
- Diarrhea
- Swelling resulting from extremity fluid retention, sometimes known as peripheral edema
Though less common, more major side effects are possible. Discuss any possible side effects with your doctor. Tell your doctor right away if you have any unexpected or concerning symptoms while using Evrenzo.
When is Evrenzo 20mg Not Recommended?
Not everyone fits Evrenzo 20 mg. In some cases, including these, it is contraindicated:
- Patients past pulmonary embolism, myocardial infarction, or cerebral infarction
- Patients with uncontrollably high blood pressure
- Women who are either pregnant or nursing
- Patients having known sensitivity to either roxadustat or either of the excipients
Before beginning Evrenzo 20 mg, be sure your doctor is aware of any underlying medical conditions you have or other medications you take. They can evaluate your unique situation and decide whether Evrenzo might be suitable for you.
Important Information About Evrenzo 20mg
This material is meant for educational only use and for general knowledge. Professional medical advice cannot be replaced by anything. Before beginning any new medication—including Evrenzo 20 mg—always see your doctor. Depending on your particular medical history and health requirements, they can offer tailored advice.
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