Indications
- treatment of latent iron deficiency;
- treatment of iron deficiency anemia;
- prevention of iron deficiency during pregnancy.
$22.00
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Indications for use: |
Inside, during or immediately after a meal.
Ferrum Lek chewable tablets can be chewed or swallowed whole.
The daily dose can be divided into several doses or taken at one time.
The dose and duration of treatment depend on the degree of iron deficiency.
The enclosed measuring spoon is used for precise dosing of Ferrum Lek syrup.
Iron deficiency anemia
The duration of treatment is about 3-5 months. After normalization of hemoglobin levels, you should continue taking the drug for several more weeks to replenish iron reserves in the body.
Children over 12 years of age, adults and breast-feeding mothers: 1-3 chewable tablets or 10-30 ml (2-6 scoops) of Ferrum Lek syrup.
Latent iron deficiency
The duration of treatment is about 1-2 months.
Children over 12 years of age, adults and breast-feeding mothers: 1 tablet per day.
Pregnant women
with iron deficiency anemia: 2-3 chewable tablets a day until the hemoglobin level returns to normal. After that, you should continue to take 1 chewable tablet a day, at least until the end of pregnancy, to replenish iron reserves in the body.
Latent iron deficiency and prevention of iron deficiency: one chewable Ferrum Lek tablet per day.
Daily doses of Ferrum Lek for the prevention and treatment of iron deficiency in the body
Patientsform of preparation Iron-deficient anaemia Latent iron deficiTprophylaxis of iron deficitdetails up to 1 yearasyrope 2.5-5 ml (25-50 mg of iron)– Children 1-12 years old-5-10 ml drop (50-100 mg of iron)2.5-5 ml (25-50 mg of iron)-Children over 12 years of age, adults, nursing mothers chewable tablets 1-3 tablets 1 tablet-Syrup 10-30 ml (100-300 mg of iron)5-10 ml (50-100 mg of iron)- Pregnant women chewable tablets 2-3 TABLETS 1 TABLET 1 tabletsirope 20-30 ml (200-300 mg of iron)10 ml (100 mg of iron)5-10 ml (50-100 mg of iron)
(- ) Due to the fact that low doses of iron are required for this group of patients, it is not recommended to use tablets or syrup in these cases.
With caution: bronchial asthma; chronic polyarthritis; cardiovascular insufficiency; low ability to bind iron and / or folic acid deficiency.
1 chewable tablet contains:
Active ingredient:
iron (in the form of iron (III) hydroxide polymaltosate) 100 mg;
Auxiliary substances:
chocolate essence,
aspartame (E 951),
talc,
macrogol 6000,
dextrates
1 chewable tablet contains:
Active ingredient:
iron (in the form of iron (III) hydroxide polymaltosate) 100 mg;
Auxiliary substances:
chocolate essence,
aspartame (E 951),
talc,
macrogol 6000,
dextrates
Ferrum Lek is an anti-anemic drug.
Pharmacodynamics
The molecular weight of the complex is so large-about 50 kDa-that its diffusion through the gastrointestinal mucosa is 40 times slower than that of divalent iron. The complex is stable and does not release iron ions under physiological conditions. The iron of the multicore active zones of the complex is bound together in a structure similar to that of the natural iron compound ferritin. Due to this similarity, the iron of this complex is absorbed only by active absorption. Iron-binding proteins located on the surface of the intestinal epithelium absorb iron (III) from the complex through competitive ligand exchange. Absorbed iron is mainly deposited in the liver, where it binds to ferritin. Later in the bone marrow, it is incorporated into hemoglobin.
Iron (III) Complex polymaltose hydroxide does not have the pro-oxidant properties inherent in iron (II) salts.
Pharmacokinetics
Studies using the double isotope method (55Fe and 59Fe) showed that iron absorption, measured by the level of hemoglobin in red blood cells, is inversely proportional to the dose taken (the higher the dose, the lower the absorption). There is a statistically negative correlation between the degree of iron deficiency and the amount of iron absorbed (the higher the iron deficiency, the better the absorption). Most iron is absorbed in the duodenum and jejunum.
The remaining (unabsorbed) iron is excreted in the faeces. Its excretion with exfoliating cells of the gastrointestinal tract and skin epithelium, as well as with sweat, bile and urine, is approximately 1 mg of iron per day. In women, there is an additional loss of iron during menstruation, which must be taken into account.
In the course of controlled studies in pregnant women (II, III trimesters of pregnancy), no negative effects on the body of the mother and fetus were noted.
No harmful effects on the fetus were detected when taking medications in the first trimester of pregnancy.
With caution: bronchial asthma; chronic polyarthritis; cardiovascular insufficiency; low ability to bind iron and / or folic acid deficiency.
The reported side effects were mostly mild and transient.
According to WHO, adverse reactions are classified according to their frequency as follows: very common (≥1/10), common (≥1/100,
From the gastrointestinal tract: very rarely — abdominal pain, nausea, constipation, diarrhea, dyspepsia, vomiting, fecal discoloration (due to the removal of non-absorbed iron, has no clinical significance).
From the skin and subcutaneous tissue: very rarely-urticaria, rash, itchy skin.
Interaction with other drugs or food products was not detected.
Simultaneous use with parenteral iron preparations and other oral preparations of iron (III) hydroxide polymaltosate is not recommended due to the pronounced inhibition of the absorption of oral iron.
Inside, during or immediately after a meal.
Ferrum Lek chewable tablets can be chewed or swallowed whole.
The daily dose can be divided into several doses or taken at one time.
The dose and duration of treatment depend on the degree of iron deficiency.
The enclosed measuring spoon is used for precise dosing of Ferrum Lek syrup.
Iron deficiency anemia
The duration of treatment is about 3-5 months. After normalization of hemoglobin levels, you should continue taking the drug for several more weeks to replenish iron reserves in the body.
Children over 12 years of age, adults and breast-feeding mothers: 1-3 chewable tablets or 10-30 ml (2-6 scoops) of Ferrum Lek syrup.
Latent iron deficiency
The duration of treatment is about 1-2 months.
Children over 12 years of age, adults and breast-feeding mothers: 1 tablet per day.
Pregnant women
with iron deficiency anemia: 2-3 chewable tablets a day until the hemoglobin level returns to normal. After that, you should continue to take 1 chewable tablet a day, at least until the end of pregnancy, to replenish iron reserves in the body.
Latent iron deficiency and prevention of iron deficiency: one chewable Ferrum Lek tablet per day.
Daily doses of Ferrum Lek for the prevention and treatment of iron deficiency in the body
Patientsform of preparation Iron-deficient anaemia Latent iron defici Tprophylaxis of iron deficitdetails up to 1 yearasyrope 2.5-5 ml (25-50 mg of iron)– Children 1-12 years old-5-10 ml drop (50-100 mg of iron)2.5-5 ml (25-50 mg of iron)-Children over 12 years of age, adults, nursing mothers chewable tablets 1-3 tablets 1 tablet-Syrup 10-30 ml (100-300 mg of iron)5-10 ml (50-100 mg of iron)- Pregnant women chewable tablets 2-3 TABLETS 1 TABLET 1 tabletsirope 20-30 ml (200-300 mg of iron)10 ml (100 mg of iron)5-10 ml (50-100 mg of iron)
(- ) Due to the fact that low doses of iron are required for this group of patients, it is not recommended to use tablets or syrup in these cases.
Symptoms: when overdosing on Ferrum Lek syrup or chewable tablets, there were no signs of intoxication or excess iron in the body, since iron from the Active ingredient is not present in the gastrointestinal tract in free form and is not absorbed by passive diffusion.
Treatment: symptomatic; as an antidote, deferoxamine is administered intravenously slowly (15 mg/kg/h), depending on the severity of overdose, but not more than 80 mg/kg/day. Hemodialysis is ineffective.
For children under 12 years of age, due to the need to prescribe low doses of the drug, it is preferable to prescribe Ferrum Lek in the form of syrup.
Neither chewable tablets nor Ferrum Lek syrup cause tooth enamel staining.
In cases of anemia caused by an infectious or malignant disease, iron accumulates in the reticulo-endothelial system, from which it is mobilized and disposed of only after the underlying disease is cured.
When using Ferrum Lek, the stool may turn dark, which does not have any clinical significance. Taking iron supplements does not affect the results of the occult bleeding test (selective for hemoglobin).
Notice for diabetics: 1 chewable tablet contains 0.04 XE.
Notice for patients with phenylketonuria: Ferrum Lek contains aspartame (E951), a source of phenylalanine, in an amount equivalent to 1.5 mg per tablet.
Influence on the ability to drive a car or perform work that requires an increased rate of physical and mental reactions. The drug does not affect the ability to concentrate attention.
Chewable tablets
At a temperature not exceeding 25 °C.
life is 3 years.
Iron III hydroxide polymaltose
By prescription
tablets for resorption
Nursing mothers as prescribed by a doctor, Children as prescribed by a doctor, Pregnant women as prescribed by a doctor, Adults as prescribed by a doctor, Children over 12 years of age
Prevention of Iron Deficiency, Anemia
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