Flamax forte, pills 100mg, 20pcs

Composition

1 film-coated tablet contains 100 mg of ketoprofen;

Auxiliary substances:

lactose monohydrate,

rice starch,

croscarmellose sodium,

povidone,

microcrystalline cellulose,

magnesium stearate,

sodium lauryl sulfate,

colloidal silicon dioxide,

hypromellose,

macrogol 6000,

talc,

titanium dioxide,

diamond blue.

Pharmacological action

Flamax Forte is a nonsteroidal anti-inflammatory drug, a derivative of propionic acid.

It has analgesic, anti-inflammatory and antipyretic effects, suppresses platelet aggregation.

Ketoprofen acts on the cyclooxygenase and lipoxygenase components of arachidonic acid metabolism and inhibits the synthesis of prostaglandins, leukotrienes, and thromboxanes.

The analgesic effect is caused by both central and peripheral mechanisms.

It has anti-radikinin activity, stabilizes lysosomal membranes.

Indications

Inflammatory and degenerative diseases of the musculoskeletal system:

• rheumatoid arthritis, psoriatic arthritis,
• ankylosing spondylitis,
• gouty arthritis (with an acute attack of gout, fast-acting dosage forms are preferred),
• osteoarthritis.

Pain syndrome:

• myalgia,
• ossalgia,
• neuralgia,
• tendinitis,
• arthralgia,
• bursitis,
• sciatica,
• adnexitis,
• otitis media,
• headache and toothache,
• cancer,
• post-traumatic and postoperative pain syndrome accompanied by inflammation.

Use during pregnancy and lactation

Flamax forte is contraindicated in pregnancy, lactation and children under 15 years of age.

Contraindications

• erosive and ulcerative lesions of the gastrointestinal tract in the acute phase
• of “aspirin” asthma
• severe liver and/or kidney function disorders
• hypersensitivity to the drug Flamax forte, hemorrhoids for the use of candles, skin diseases and wounds for the use of gel.

Side effects

• nausea,
• vomiting,
• constipation or diarrhea,
• stomach pain
• headaches,
• dizziness,
• drowsiness
• allergic reactions in the form of skin rash
• erosive and ulcerative lesions of the gastrointestinal tract
• bleeding of the gastrointestinal tract.

Interaction

Reduces the effectiveness of uricosuric drugs, increases the effect of anticoagulants, antiplatelet agents, fibrinolytics, ethanol, side effects of glucocorticosteroids and mineralocorticosteroids, estrogens; reduces the effectiveness of antihypertensive drugs and diuretics.

Concomitant use with other NSAIDs, glucocorticosteroids, ethanol, and corticotropin may lead to ulceration and gastrointestinal bleeding, and increase the risk of developing renal dysfunction.

Concomitant use with oral anticoagulants, heparin, thrombolytics, antiplatelet agents, cefaperazone, cefamandol and cefotetan increases the risk of bleeding.

Increases the hypoglycemic effect of insulin and oral hypoglycemic drugs (dose recalculation is necessary). Inducers of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites.

Co-use with sodium valproate causes a violation of platelet aggregation.

Increases plasma concentrations of verapamil and nifedipine, lithium preparations, and methotrexate. Antacids and colestyramine reduce absorption.

Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.

How to take, course of use and dosage

Adults are prescribed Flamax forte orally in an initial daily dose of 300 mg in 2-3 divided doses.

The maximum daily dose is 300 mg.

Overdose

Symptoms:  drowsiness, nausea, vomiting, abdominal pain, bleeding, and impaired liver and kidney function may occur.

Treatment is symptomatic:  gastric lavage and / or activated charcoal and / or other sorbents. There is no specific antidote.

Special instructions

With extreme caution, the drug Flamax forte is prescribed to patients with liver and kidney diseases, diseases of the gastrointestinal tract and immediately after serious surgical interventions.

During treatment with the drug, systematic monitoring of liver and kidney function is necessary.

Concomitant use with anticoagulants increases the risk of bleeding.

Form of production

Film-coated tablets.

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 25 °C

Shelf life

3 years

Active ingredient

Ketoprofen

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Description

Pregnant women as prescribed by a doctor, Children as prescribed by a doctor, For adults, Nursing mothers as prescribed by a doctor, Children over 15 years of age

Indications

Lumbago, Trigeminal Neuralgia, Bursitis, Rheumatoid arthritis, Osteoarthritis, Sciatica, Swelling after injuries and operations, Osteochondrosis, Gout, Osteoarthritis, Bruises, Myositis, Arthritis