Flavamed forte oral solution 30mg/5ml vial, 100ml

Composition

5 ml of the solution contains:

Active ingredient:

ambroxol hydrochloride – 30.00 mg;

Auxiliary substances:

benzoic acid (E 210),

glycerin (85%),

sorbitol solution, does not crystallize (E 420),

hydroxyethylcellulose,

purified water,

raspberry flavor No. 516028.

Pharmacological action

Ambroxol is an active N-demethylated metabolite of Bromhexinee. It has secretomotor, secretolytic and expectorant effects.

It stimulates the serous cells of the glands of the bronchial mucosa, increasing the content of mucosal secretions and, thus, normalizes the disturbed ratio of serous and mucosal components of sputum.

Ambroxol increases the content of mucosal secretions, the formation of surfactant and its content in the alveoli and bronchi. Increases motor activity of the ciliated epithelium, increases mucociliary sputum transport.

On average, when taken orally, the effect occurs in 30 minutes, the duration of action is 6-12 hours, depending on the single dose.

Indications

Violation of sputum secretion and transport in acute and chronic respiratory diseases:

• acute and chronic bronchitis;
• pneumonia;
• chronic obstructive pulmonary disease;
• bronchial asthma;
• bronchiectatic disease.

Contraindications

• hypersensitivity to ambroxol and other components of the drug (see the section “Composition”);
• hereditary fructose intolerance;
• I trimester of pregnancy and the period of breastfeeding.

Caution

• violation of the motility of the bronchi and increased mucus secretion (for example, when a rare syndrome of primary cilia dyskinesia);
• severe renal insufficiency (creatinine clearance less than 30 ml/min) or severe hepatic impairment;
• ulcer disease of stomach and duodenum, including in the anamnesis;
• II and III trimester of pregnancy;
• children’s age up to 2 years (only by prescription).

Side effects

• sometimes (≥0.1, ; 
• very rare (

Interaction

With the combined use of Flavamed Forte and antitussive agents that depress the cough reflex, dangerous stagnation of secretions can occur, so you need to carefully weigh the decision on the feasibility of this combination.

Concomitant use of ambroxol with antibiotics (amoxicillin, cefuroxime, erythromycin) increases the concentration of the latter in sputum.

How to take, course of use and dosage

Flavamed Forte is intended for oral use. The drug is taken orally after a meal, washed down with a glass of water. To dispense the drug, use a measuring spoon in the package, which is marked 1/4 and 1/2, respectively, according to the amount of its filling, and holds 5 ml of the solution, which corresponds to 30 mg of ambroxol hydrochloride.

The secretolytic effect of ambroxol hydrochloride is maintained if the body receives a sufficient amount of fluid, so the patient should consume a lot of fluids during treatment.

Children under the age of 2 years are prescribed 1/4 measuring spoon 2 times a day; at the age of 2-5 years-1/4 measuring spoon 3 times a day; at the age of 6-12 years-1/2 measuring spoon of the solution 2-3 times a day.

Adults and adolescents over the age of 12 years — 1 measuring spoon of the solution 3 times a day for the first 2-3 days, then-1 measuring spoon 2 times a day. If necessary, adults can take 2 scoops 2 times a day.

The duration of treatment is determined by the doctor depending on the course of the disease, but the drug should not be used for more than 4-5 days without a doctor’s supervision.

Overdose

Serious manifestations of intoxication with an overdose of ambroxol were not noted.

Symptoms. There were reports of short-term anxiety and diarrhea. With a significant overdose, hypersalivation, nausea, vomiting, and a decrease in blood pressure may occur.

Treatment. Emergency measures, such as inducing vomiting and gastric lavage, are not indicated, they are used only in cases of significant overdose. If necessary, symptomatic therapy is recommended.

Special instructions

In severe renal insufficiency, the possibility of accumulation of ambroxolol metabolites formed in the liver should be considered.

To maintain the secretolytic effect of ambroxol during the period of taking the drug, it is necessary to ensure the intake of fluid in the body in sufficient quantities.

When prescribing the drug to patients with diabetes mellitus, it should be borne in mind that in 5 ml of a solution (1 mern. spoon) contains 1.75 g of sorbitol, which corresponds to 0.15 XE.

Influence on the ability to drive vehicles and other mechanisms that require increased concentration of attention

Not installed.

Form of production

Solution

Active ingredient

Ambroxol

Dosage form

oral solution