ATC code | B01AB07 |
---|---|
CAS Number | 168087-92-9 |
Other product names | Arixtra, Fondaparinux Sodium Aspen, Pr Fondaparinux Sodium Injection |
Dosage form | Solution for injection |
Active ingredient | Fondaparinux sodium |
Other ingredients | Sodium chloride, water for injections, hydrochloric acid and/or sodium hydroxide to adjust the pH |
Pharmacological classification | Antithrombotic agent |
Pharmacological action | Selective inhibitor of factor Xa, anticoagulant |
Storage conditions | Store in a refrigerator (2°C to 8°C). Do not freeze. |
Fondaparinux Sodium Solution: What It Is and Why It’s Used
Describes Fondaparinux Sodium Solution.One strong synthetic antithrombotic medicine used to prevent and treat blood clots is fondaparinux sodium solution. It is a member of a class of medications sometimes referred to as factor Xa inhibitors, which disrupt the function of factor Xa, a fundamental enzyme in the blood clotting cascade. Patients with deep vein thrombosis (DVT), pulmonary embolism (PE), and those having specific surgeries to prevent blood clots are typically prescribed fondaparinux.
Pre-filled syringes with a clear, colorless to somewhat yellow fluid contain this medicine. Strong anticoagulant fondaparinux sodium is the active ingredient; it acts by preventing blood clot formation.
Fondaparinux Sodium Solution Composition
Fondaparinux sodium injections 2.5 mg of fondaparinux sodium in 0.5 mL of an isotonic sodium chloride solution is contained in every single-dose, prefilled syringe. To balance the pH, the solution also includes sodium chloride, water for injections, and hydrochloric acid or sodium hydroxide.
Benefits and Effects of Fondaparinux Sodium Solution
Patients who run a risk of blood clots or those already suffering from these diseases may find great advantages from fondaparinux sodium solution. The following are the main consequences of this medicine:
- Fondaparinux sodium dramatically stops blood clots from forming in the veins, therefore lowering the risk of DVT and PE.
- Treatments for current blood clots in the lungs and legs can also be found here.
- Sometimes fondaparinux sodium is used to prevent stroke in people with atrial fibrillation, a disorder that raises the chance of blood clots developing in the heart.
- Fondaparinux sodium is a handy and quick treatment since it is given by subcutaneous injection.
What is Fondaparinux Sodium Solution Used For?
Mostly used for the following, fondaparinux sodium solution serves:
- Fondaparinux sodium helps patients having hip or knee replacement surgery avoid blood clots developing in the deep veins of their legs.
- Avoiding Pulmonary Embolism (PE): Preventing DVT helps Fondaparinux sodium also lowers the chance of PE, in which case a blood clot moves from the legs to the lungs.
- Fondaparinux sodium can be used to treat current DVT, therefore dissolving the blood clot and avoiding more difficulties.
- Treatment of pulmonary embolism (PE) can also be applied to dissolve the clot in the lungs and lower the risk of further embolization.
Fondaparinux Sodium Solution: Usage Guidelines
One uses subcutaneous injection to deliver fondaparinux sodium solution. The particular indication for use and the state of the individual patient will determine the dosage and frequency of administration. The suitable dosage and timetable for your therapy will be decided upon by your healthcare professional.
Dosage and Administration of Fondaparinux Sodium Solution
The weight, medical condition, and particular indication for usage of the patient will affect the advised dosage of Fondaparinux sodium solution. The proper amount and frequency of administration will be decided upon by your healthcare professional.
Potential Side Effects of Fondaparinux Sodium Solution
Though not everyone experiences them, fondaparinux sodium solution might have adverse effects, just as any drug. Several typical side effects consist in:
- Being an anticoagulant, Fondaparinux sodium raises the risk of bleeding.
- Patients may have redness, discomfort, or swelling at the injection site.
- Some patients might have headaches.
Rarely, more major side effects can arise, including:
- Fondaparinux sodium can raise the risk of bleeding around the spinal cord in individuals undergoing neuraxial anesthesia, therefore causing paralysis.
- A rare but dangerous disorder known as Heparin-Induced Thrombocytopenia (HIT) can be brought on by fondaparinux sodium-lowering platelet count, so raising bleeding risk.
Tell your doctor right away if you have any unusual or severe side effects.
When Should You Avoid Fondaparinux Sodium Solution?
Not every patient should use Fondaparinux sodium solution. In the following circumstances, it is contraindicated:
- Fondaparinux sodium should not be advised to patients with severe renal impairment (creatinine clearance less than 30 mL/min) since it can build up in the body and raise bleeding risk.
- Patients with active bleeding should avoid fondaparinux sodium since it raises their risk of more bleeding.
- Fondaparinux sodium should not be advised to people who have lately had major surgery since it raises their risk of bleeding.
- History of HIT: Fondaparinux sodium should not be used by patients having heptin-induced thrombocytopenia (HIT).
Before beginning therapy with Fondaparinux sodium solution, be sure your healthcare provider is aware of any pre-existing medical conditions or drugs you are taking.
How to Store Fondaparinux Sodium Solution
Store the Fondaparinux sodium solution refrigerated between 2°C and 8°C (36°F and 46°F). Maintaining their original container will help to guard the syringes against light and moisture. Freeze the solution not at all.
Important Information About Fondaparinux Sodium Solution
The following details on Fondaparinux sodium solution are really important to grasp:
- If the solution seems discolored or foggy, do not use it.
- Should the expiration date have passed, avoid using the solution.
- Always closely follow the advice of your healthcare provider.
- See your healthcare professional for direction should you miss a dosage.
- Dont stop using Fondaparinux sodium solution without first seeing your doctor.
- Keep childrens reach free from the Fondaparinux sodium solution.
- See your healthcare practitioner if you have questions or concerns regarding Fondaparinux sodium solution.
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