Composition
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of 1 g of ointment for external use contains:
Active ingredient:
fusidic acid hemihydrate (in terms of anhydrous acid) 20.4 mg (equivalent to 20 mg of anhydrous fusidic acid);
Auxiliary substances:
lanolin (contains no more than 200 ppm of butylhydroxytoluene) – 46 mg;
cetyl alcohol-4 mg;
liquid paraffin (contains about 10 ppm of alpha-tocopherol) – 140 mg;
soft white paraffin (contains about 10 ppm of alpha-tocopherol) – 790 mg
Pharmacological action
Fucidin has an antibacterial effect.
Fusidic acid belongs to the group of fusidins, antimicrobial compounds whose mechanism of action is associated with a violation of protein synthesis in the bacterial cell.
Fusidic acid is susceptible to gram-positive bacteria and gram-negative cocci, such as Staphylococcus aureus, Staphylococcus epidermidis (including methicillin-resistant strains), Nocardia asteroides, Corynebacterium minutissimum, Streptococcus pyogenes, Pseudomonas spp., Clostridium spp., Neisseria meningitidis, Neisseria gonorrhoeae.
It is inactive against Escherichia coli, Salmonella spp., Proteus spp. and other gram-negative bacteria, as well as protozoa and fungi.
Pharmacokinetics
The permeability of fusidic acid through intact skin is low. It does not enter the systemic circulation.
Indications
Skin infections caused by bacteria sensitive to fusidic acid.
Contraindications
Hypersensitivity to the components of the drug Fucidin.
With caution: pregnancy, lactation.
Side effects
From the skin and subcutaneous tissues: infrequently-rash (erythematous, maculopapular, pustular), skin irritation, including pain, burning sensation, tingling sensation on the skin, itching, dry skin, contact dermatitis; rarely-urticaria, angioedema, eczema, periorbital edema, erythema.
Immune system disorders: rarely-allergic reactions.
From the side of the organ of vision: rarely – irritation of the conjunctiva.
If any of the side effects listed in the instructions get worse, or the patient notices any other side effects that are not listed in the instructions, you should inform your doctor.
How to take, course of use and dosage
Adults and children from birth to 18 years of age. Apply to the affected areas of the skin in a thin layer 3-4 times a day.
When using gauze bandages, the frequency of application can be reduced to 1-2 times a day.
The duration of treatment depends on the form and severity of the disease and averages 7-14 days.
Special instructions
Do not apply Fucidin to the skin around the eyes, as fusidic acid, if it gets into the eyes, causes conjunctival irritation.
Fucidin ointment contains lanolin and cetyl alcohol, which can cause local allergic skin reactions (for example, contact dermatitis).
When fusidic acid is used, bacterial resistance may develop. As with other antibiotics, prolonged or repeated use may increase the risk of developing antibiotic resistance.
Influence on the ability to drive vehicles and work with mechanisms. The effect on the ability to drive vehicles and complex mechanisms was not revealed.
Form of production
Ointment for external use
Storage conditions
At a temperature not exceeding 25 °C.
Shelf
life is 3 years.
Active ingredient
Fusidic acid
Conditions of release from pharmacies
By prescription
Dosage form
ointment
Description
For adults as prescribed by a doctor, For Children as prescribed by a doctor, For children from birth
Indications
Skin Infections
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Side effects of Fucidin, 2% ointment, 15g.
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