ATC code | J06AA02 |
---|---|
CAS Number | 74298-69-8 |
Other product names | Gabriglobin-IgG, Gamunex, Carimune, Privigen, Hizentra, Gammaplex |
Dosage form | Solution for infusion |
Active ingredient | Human normal immunoglobulin |
Other ingredients | Glycine, sodium acetate, sodium chloride, polysorbate 80, D-sorbitol |
Pharmacological classification | Immunoglobulin |
Pharmacological action | Replacement therapy, prevention of infections, treatment of primary immunodeficiency, idiopathic thrombocytopenic purpura |
Storage conditions | Store at 2-8°C, protect from light |
Gabriglobin-IgG Solution
What is Gabriglobin-IgG?
5% 50ml 1pc Gabriglobin-IgG Solution
Solution of Gabriglobin-IgG For intravenous injection, 5% 50 mL (1 pc) is a sterile, non-pyrogenic solution. This very pure immunoglobulin product offers a wide spectrum of antibodies against many bacterial and viral infections. Primary immunodeficiency, acquired immunodeficiency, and hypogammaglobulinemia are among the several immunodeficiency diseases for which Gabriglobin-IgG is suggested.
Found naturally in human blood, globin-IgG is a kind of immunoglobulin sometimes referred to as an antibody. The immune system of the body depends on immunoglobulins to fight against diseases. Extracted from human blood plasma, gabriglobin-IgG is a concentrated immunoglobulin solution. Among the most plentiful kinds of antibodies in the human body, IgG antibodies abound in it.
Gabriglobin-IgG Composition
Comprising 5% immunoglobulin human normal (IgG), gabriglobin-IgG is an intravenous infusion solution. This is a non-pyrogenic, sterile, preservative-free solution. Every vial has fifty milliliters of solution. Intravenous infusion uses a single-dose bottle for it.
Advantages and Consequences of Gabriglobin-IgG
Passive protection against several diseases is offered by gabriglobin-IgG. It acts by filling in for absent or inadequate antibodies in the body. Intravenous gabriglobin-IgG attaches to microorganisms and circulates in the bloodstream, therefore stopping their ability to start an illness. This lowers the chance of infection development and helps to boost immunity.
For What Usage is Gabriglobin-IgG?
Several immunodeficiency disorders are treated with gabriglobin-IgG; among them are:
- Fundamental immunodeficiency
- Developed immunity
- Hypogammaglobulinity
- Cidp, or chronic inflammatory demyelinating polyneuropathy:
- syndrome of Guillain-Barré
- Myasthenia Gravis
- Disease called Kawasaki
- Other diseases mediated by immunological systems
How to Apply Gabriglobin-IgG?
A healthcare provider administers gabriglobin-IgG intravenously. The patients condition and degree of immunodeficiency will determine both the amount and frequency of administration. You should pay great attention to the advice of your healthcare provider.
Dose and Administration of Gabriglobin-IgG
Gabriglobin-IgG dosage changes according to patient age, weight, and condition. For adults, the advised beginning dosage is 0.4 g/kg of body weight daily. The patients response to treatment will help one to modify the dosage.
Usually given as an intravenous infusion spread over several hours, gabriglobin-IgG Initially, the infusion rate should be moderate; subsequently, it should be progressively raised as tolerated. Throughout the infusion, the patient should be under close observation to look for any indications of side effects.
Side Effects of Gabriglobin-IgG
Gabriglobin-IgG has side effects, just as every drug. Side effects most often be minor and transient. Still, occasionally severe side effects do happen. Typical adverse effects of gabriglobin-IgG consist in:
- Acute headache
- Fevers
- Chills
- Muscle spasms
- Appetite
- Pertusiveness
- Diarrhea
- Redness
- Skin itching
Though rare, serious side effects of gabriglobin-IgG can occur. See a doctor right away if you run into any of the following negative effects:
- Trouble breathing
- Face, tongue, or lip swelling
- Hives
- Stomach discomfort
- Accelerated pulse
- Seizure
- Coma of consciousness
Gabriglobin-IgG Contraindications
Those allergic to human immunoglobulin or any component in the product should not use Gabriglobin-IgG. Patients with severe sepsis or anaphylactic shock to human blood products in past times should also avoid it. Tell your doctor whether you have any medical issues or allergies before starting Gabriglobin-IgG.
Storage Conditions
Store gabriglobin-IgG refrigerated between 2°C and 8°C (36°F and 46°F). Freeze not. Guard from light. Keep out of reach of children.
Before use, gabriglobin-IgG should be visually checked for any particle debris or discoloration. Should any exist, avoid using the solution.
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