Galazolin, nasal drops 0.05%, 10ml

Composition

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1 ml of drops contains:

Active ingredient:

xylometazoline hydrochloride;

Auxiliary substances:  

sodium hydrophosphate dodecahydrate,

sodium dihydrophosphate monohydrate,

sodium chloride,

disodium edetate

benzalkonium chloride 50%,

sorbitol,

purified water-up to 1 ml

Pharmacological action

Vasoconstrictor drug for topical use in ENT practice. Alpha-adrenomimetic from the group of imidazole derivatives. In low concentrations, it acts on α2-adrenergic receptors, in high concentrations it has an effect on α1-adrenergic receptors.

When applied topically, it causes narrowing of blood vessels, which leads to a decrease in edema and hyperemia of the nasopharyngeal mucous membranes, reduces the amount of nasal discharge, and facilitates nasal breathing in rhinitis.

The effect of the drug begins in 5-10 minutes and persists for 5-6 hours when used in the form of nasal drops and for 10 hours when used in the form of a nasal gel.

Indications

• acute rhinitis of viral or bacterial origin;
• allergic rhinitis;
• acute sinusitis;
• chronic sinusitis in the acute phase;
• pollinosis;
• otitis media (in order to reduce swelling of the nasopharyngeal mucosa and restore patency of the Eustachian tube).

Use during pregnancy and lactation

Galazoline should only be used after evaluating the risk-benefit ratio for the fetus and the mother.

Do not exceed the recommended dose during pregnancy and lactation (breastfeeding).

Contraindications

• hypersensitivity to the components of the drug;
• atrophic rhinitis;
• angle-closure glaucoma;
• arterial hypertension;
• severe atherosclerosis;
• tachycardia;
• hyperthyroidism (for nasal drops);
• surgical removal of the meninges (history);
• simultaneous reception of MAO inhibitors and a period of 14 days after their application;
• concomitant use of tricyclic antidepressants;
• pregnancy;
• children up to age 6 years (0.1% nasal drops) and 2 years (for 0.05% nasal drops);
• children under 12 years (for 0.1% gel nasal) and 3 years (for 0.05% gel nasal).

With caution, the drug should be used during lactation, with diabetes mellitus, with angina pectoris of functional class III-IV, prostatic hyperplasia, pheochromocytoma (for nasal drops), with hyperthyroidism (for nasal gel).

Side effects

Local reactions:  sometimes-burning sensation, dryness of the nasal mucosa, sneezing; rarely-reactive hyperemia (a strong feeling of nasal congestion after the effect of the drug passes).

Other services:  sometimes with a local overdose-tachycardia, increased blood pressure; very rarely-anxiety, insomnia, fatigue, headache, nausea.

How to take, course of use and dosage

Galazolin in the form of 0.05% drops is prescribed to children aged 2 to 6 years,1-2 drops in each nostril 1-2 times a day.

Galazolin in the form of nasal drops should not be used more than 3 times a day.

Special instructions

Prolonged use of Galazoline leads to a weakening of its action, the development of atrophy of the nasal mucosa and reactive hyperemia with drug-induced rhinitis.

Form of production

Nasal drops

Storage conditions

The drug should be stored in a place protected from light, inaccessible to children at a temperature of 15° to 25°C.

Shelf life

3 years

Active ingredient

Xylometazoline

Dosage form

nasal drops

Description

Nursing mothers as prescribed by a doctor, Children over 2 years of age

Indications

Allergy, Otitis Media, Pollinosis, Sinusitis, Runny Nose