Gioksizon-Akrikhin ointment 1%+3% ointment 10g, 1pc
$12.00
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| ATC code | L01XE01 |
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| CAS Number | 157319-22-3 |
| Other product names | Glivec, Imatinib mesylate, STI-571 |
| Dosage form | Capsules |
| Active ingredient | Imatinib |
| Other ingredients | Lactose monohydrate, microcrystalline cellulose, pregelatinised starch, sodium laurilsulfate, magnesium stearate, hypromellose, titanium dioxide (E171), iron oxide yellow (E172), iron oxide red (E172), gelatin |
| Pharmacological classification | Protein-tyrosine kinase inhibitor, specific for abnormal BCR-ABL tyrosine kinase produced by Philadelphia chromosome in CML/ALL |
| Pharmacological action | Inhibits activity of BCR-ABL fusion protein, resulting in both hematologic response (ie, normal cell counts in the peripheral blood and normal bone marrow morphology), as well as cytogenetic response (ie, disappearance or reduction of the Philadelphia Ph chromosome) |
| Storage conditions | Store at 25ºC (77ºF); excursions permitted to 15-30ºC (59-86ºF). Protect from moisture; do not crush tablets. Avoid direct contact or exposure to crushed tablets with the skin or mucous membranes. If such contact occurs, wash thoroughly as outlined in the references. |
Gleevec: A Targeted Therapy for Cancer
Describes Gleevec.Used to treat some forms of cancer, gleevec—also known as imatinib mesylate—is medicine. It is a member of the class of medications known as tyrosine kinase inhibitors. These medications limit the action of several enzymes, including the BCR-ABL tyrosine kinase implicated in the proliferation and dissemination of cancer cells. Being a targeted therapy, gleevec has fewer adverse effects than conventional chemotherapy medications and targets cancer cells particularly.
What is Gleevec?
The active element of gleevec capsules is imatinib mesylate. There are capsules with 100 mg, 400 mg, and 600 mg among several strengths. Every capsule also includes inactive components meant to stabilize and formulate the medicine.
Benefits and Results of Gleevec
Among the several malignancies, including chronic myeloid leukemia (CML), gleevec has proven to be successful in treating:
- Gastrointestinal stromal tumors, or GASTs
- ALL, or acute lymphoblastic leukemia:
- specific forms of myeloproliferative diseases
When Gleevec is used to treat CML, it can help to lower the amount of leukemia cells in the blood and bone marrow, improve blood counts, and lower the risk of acquiring a more severe type of the illness. Gleevec can assist people with GESTs in decreasing tumors and stopping the diseases progression.
Gleevec’s Uses
Prescription drugs used in the treatment of some forms of cancer are generic. Though it can increase patients quality of life and help to control their disease, Gleevec is not a cure for cancer.
Using Gleevec:
Usually taken orally once a day alongside a full glass of water, gleevec is The doctor decides the Gleevec dosage; it varies depending on the type of cancer being treated, the patients weight and age, and other considerations.
Dosage and Gleevec Administration:
Your doctor will decide on Gleevec dosage. You should take Gleevec exactly as directed by your doctor. Take neither more nor less of the drug than advised.
Side Effects of Gleevec
Gleevec has side effects like all drugs do. Typical side effects of Gleevec consist in:
- Apprehension
- Pertussiveness
- Diarrhea
- Muscle strains
- Weariness
- Migraine
Though rare, serious adverse effects can develop with Gleevec. These side effects could consist in:
- hepatic issues
- Lung difficulties
- Cardiovascular issues
- Hemostasis
- Fluid retention
If you have any of these adverse effects, you should get right on seeing your doctor.
Contraindications for Gleevec
Not everyone will find it appropriate. Those allergic to imatinib mesylate or any of the inactive components in Gleevec should not take it.
Furthermore, interacting with other drugs is difficult. Tell your doctor about any medication you use, including over-the-counter drugs, vitamins, and herbal supplements.
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