ATC code | A10BB01 |
---|---|
CAS Number | 10238-25-5 |
Other product names | Glyburide |
Dosage form | Tablets |
Active ingredient | Glibenclamide |
Other ingredients | Lactose, maize starch, povidone K30, magnesium stearate |
Pharmacological classification | Sulfonylurea |
Pharmacological action | Stimulates insulin secretion, reduces basal hepatic glucose production, enhances peripheral insulin action |
Storage conditions | Store below 25°C |
Glibenclamide: What is it?
Glibenclamide is a medication used to treat type 2 diabetes. It belongs to a class of drugs called sulfonylureas. These drugs work by stimulating the pancreas to produce more insulin, which helps lower blood sugar levels. Glibenclamide is typically used in combination with diet and exercise to help regulate blood sugar.
Glibenclamide Composition
- Each Glibenclamide tablet contains 3.5 mg of Glibenclamide.
- A pack contains 120 tablets.
- This medication should be taken as directed by your doctor and is for oral consumption.
Advantages and Consequences of Glibenclamide
Glibenclamide helps control blood sugar levels in individuals with type 2 diabetes. This can help prevent complications associated with the condition, including:
- Kidney disease
- Heart disease
- Stroke
- Nerve damage
Taking Glibenclamide as prescribed can significantly improve your overall health and quality of life.
How to Use Glibenclamide
Glibenclamide is typically taken once or twice a day, with or without food. The dosage will depend on your individual needs and response to the medication. It is essential to follow your doctors instructions carefully. Never take more or less of this medication than prescribed.
Amount and Method of Administration
- Glibenclamide treatment usually starts with a daily dose of 2.5 to 5 mg, taken with breakfast or the first substantial meal.
- If you are sensitive to hypoglycemic medications, you may start with a lower daily dose of 1.25 mg.
- The typical maintenance dose ranges from 2.5 to 15 mg daily, usually taken in one or two divided doses.
- The maximum daily dose is 20 mg.
Side Effects of Glibenclamide
Like all medications, Glibenclamide can have side effects. Some of the most common adverse effects include:
- Low blood sugar (hypoglycemia)
- Headache
- Disorientation
- Nausea
- Vomiting
- Stomach upset
- Weight changes
If you experience any of these side effects, consult your doctor.
In rare cases, Glibenclamide can have more serious adverse effects, including:
- Allergic reactions
- Liver problems
- Blood abnormalities
Who Should Not Use Glibenclamide
Glibenclamide is not suitable for everyone. You should not use this medication if you:
- Are allergic to Glibenclamide or other sulfonylureas.
- Have type 1 diabetes.
- Are dealing with diabetic ketoacidosis, a serious diabetes complication.
- Are dealing with diabetic coma or pre-coma.
- Have a rare hereditary condition called acute porphyria.
- Are dealing with a severe infection.
- Have extreme thyroid function deficiency.
- Have extreme adrenal function loss.
- Are breastfeeding.
Before using Glibenclamide, be sure to discuss any of these conditions with your doctor. They can determine if this medication is appropriate and safe for you.
Glibenclamide Storage
Store Glibenclamide at room temperature, between 15°C and 30°C. Keep it dry, away from direct sunlight and moisture. Store it out of reach of children and pets.
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