Guttasil, oral pills 7.5mg 30pcs

Composition

1 tab. sodium picosulfate 7.5 mg

Excipients:

sorbitol 460 mg,

sodium methylparaoxybenzoate 2.0 mg,

hydrochloric acid 1 M to pH 6.0-7.0,

water for injection up to 1 ml

Pharmacological action

Guttasil is a laxative.

Indications

Constipation or cases requiring relief of defecation (hemorrhoids, proctitis, anal fissures, preparation for surgery, instrumental and X-ray examinations).

Contraindications

• hypersensitivity to sodium picosulfate and the other components of the drug;
• intestinal obstruction;
• acute inflammatory bowel disease and acute diseases of the abdominal organs (including acute appendicitis, ulcerative colitis, peritonitis);
• acute abdominal pain accompanied with nausea and vomiting, which may indicate an acute inflammatory disease, severe dehydration;
• pregnancy (I trimester);
• lactation.

Side effects

From the side of the skin:  skin rash, urticaria, pruritus.

From the side of the water-electrolyte balance:  loss of potassium, sodium, and other electrolytes, and possible dehydration.

From the digestive system:  dyspeptic symptoms, vomiting, nausea, abdominal cramps and pain, diarrhea, flatulence, pain in the stomach and anus, increased intestinal motility, which disappear with a decrease in the dose of the drug.

From the immune system:  allergic reactions, angioedema.

From the central nervous system:  headache, fatigue, drowsiness, convulsions.

Interaction

An electrolyte imbalance can lead to a decrease in tolerance to cardiac glycosides.

Diuretics or corticosteroids may increase the severity of hypokalemia caused by the use of Guttasil in high doses.

Simultaneous treatment with antibiotics may reduce the laxative effect of the drug.

How to take, course of use and dosage

Inside, for the night (so that the chair is ready the next morning).

Overdose

Symptoms:

High doses of Guttasil may cause fluid bowel movements, abdominal cramps (colic), and clinically significant disturbances in the water-electrolyte balance (hypokalemia, loss of other electrolytes and fluids), and ischemia of the colon mucosa. Prolonged overdose leads to the development of chronic diarrhea and abdominal pain, hypokalemia, secondary hyperaldosteronism, possible kidney damage and the development of nephrolithiasis, metabolic alkalosis, hypokalemia and muscle weakness as a result of hypokalemia.

Treatment:  

gastric lavage, use of enterosorbents (activated charcoal), symptomatic treatment (correction of water and electrolyte balance, use of antispasmodics).

Special instructions

Like other laxatives, Guttasil should not be taken daily for a long time. If you need to take daily laxatives, you should find out the cause of constipation. Long-term use of laxatives can lead to electrolyte imbalance and hypokalemia, as well as cause addiction and constipation due to the rebound effect.

Guttasil is effective in relieving constipation in cancer patients receiving high doses of opioids.

The drug contains sorbitol, so patients with rare hereditary problems of fructose intolerance are not recommended to take it.

Influence on the ability to drive vehicles and work with mechanisms.

In therapeutic doses, the drug does not affect the ability to drive vehicles and work with other mechanisms.

Active ingredient

Sodium Picosulfate

Dosage form

Tablets

Description

Children over 10 years of age, For adults, Pregnant women in the second and third trimester as prescribed by a doctor, Nursing mothers as prescribed by a doctor

Indications

Constipation, Hemorrhoids, Preparation for ultrasound and X-ray of the abdominal cavity