Gyno-Pevaryl, vaginal suppositories 50mg, 15pcs

Composition

Active ingredient:

econazole nitrate 50 mg;

Auxiliary substances:

solid fat.

Pharmacological action

Gyno-pevaril is an antifungal drug.

Econazole nitrate has a broad spectrum of action and is active against dermatophytes, yeast and mold fungi. It also has clinically significant activity against gram-positive bacteria.

Econazole nitrate damages cell membranes, which leads to increased permeability of the fungal cell. The target of action of econazole nitrate is acyl groups of unsaturated fatty acids that are part of membrane phospholipids.

Indications

Vulvo-vaginal mycoses.

Use during pregnancy and lactation

With intravaginal use of Gyno-Pevaryl econazole, nitrate is absorbed from the vagina into the systemic circulation, so the drug should not be used in the first trimester of pregnancy, except in cases of extreme necessity.

In the second and third trimesters, Gyno-Pevaril can be used if the potential benefit of therapy for the mother outweighs the possible risk to the fetus.

It is not known whether econazole nitrate penetrates into breast milk. Breast-feeding should be discontinued for the duration of the drug use.

Contraindications

Hypersensitivity to the components of the drug.

Interaction

There are no data on the drug interaction of the drug.

How to take, course of use and dosage

One 50 mg suppository is injected deep into the vagina 1 time / day before bedtime for at least 14 days. It is necessary to carry out a full course of treatment, even if the subjective symptoms disappear (pruritus, leukorrhea).

Overdose

There are no reports of overdose of econazole nitrate.

– Symptoms: accidental ingestion of Gyno-Pevaril may cause nausea, vomiting, and diarrhea. – Treatment: gastric lavage, ingestion of activated charcoal, carrying out symptomatic therapy.

Special instructions

If severe irritation occurs, treatment with Gyno-Pevaril should be discontinued.

Patients who are sensitive to imidazoles may also be hypersensitive to econazole nitrate.

Concomitant use of latex condoms or diaphragms and intravaginal medications to treat infections may reduce the effectiveness of latex barrier contraceptives. Therefore, Gino-Pevaril is not recommended to be used simultaneously with a diaphragm or condom.

Gyno-Pevaril should not be used in combination with other oral or external medications for the treatment of genital diseases.

Intravaginal medications may inactivate the spermicidal contraceptive.

The drug is not intended for oral use.

– Use in elderly patients Data on the use of Gyno-Pevaril in elderly patients (older than 65 years) are insufficient.

– Use in pediatrics There are no data on the safety and efficacy of Gyno-Pevaril in children under 16 years of age.

Product form

vaginal suppositories

Storage conditions

At a temperature of 15-30 °C

Shelf life

3 years

Active ingredient

Econazole

Conditions of release from pharmacies

By prescription

Dosage form

vaginal suppositories

Description

Pregnant women as prescribed by a doctor, For women

Indications

Thrush, Vaginitis