Hepatrombin G, ointment for rectal and external use 20g

Composition

>

of 1 g of the drug contains:

active ingredients:

Sodium heparin — 65 IU;

(1 IU of sodium heparin — anticoagulant activity, corresponds to the activity of 0.0077 mg of the II International Standard of Heparin (WHO))

Prednisolone acetate — 2,233 mg;

Lauromacrogol 600-30.00 mg.

Auxiliary substances:  

Solid paraffin

Liquid paraffin

Lanolin

Silicon dioxide is colloidal.

Pharmacological action

” Combined drug. Heparin is a direct-acting anticoagulant that, when applied externally, has antithrombotic, anti-exudative and moderate anti-inflammatory effects; promotes the regeneration of connective tissue, prevents blood coagulation in hemorrhoids.

Prednisone is a glucocorticoid that has anti-inflammatory, anti-exudative and anti-allergic effects; reduces inflammation and associated sensations (itching, burning, pain) in the anorectal area.

Polydocanol has a local anesthetic effect and provides sclerosis of hemorrhoids. “

Active ingredients

Heparin Sodium + Prednisone

Indications

External and internal hemorrhoids.

Thrombophlebitis of the hemorrhoidal veins of the anus.

Fistulas, eczema, and pruritus in the anus.

Anal fissures.

preparation for surgery in the anorectal area.

as part of the complex therapy of thrombosed or operated hemorrhoids.

Contraindications

• hypersensitivity to the components of the drug;
• bacterial, viral, fungal skin lesions;
• tuberculosis;
• syphilis;
• skin tumors (anorectal zone);
• predisposition to bleeding;
• reactions to vaccination;
• I trimester of pregnancy.

Side effects

Systemic reactions: allergic reactions, hyperemia of the skin. Long-term use and/or application on large surfaces may result in systemic side effects: slow crack regeneration, swelling.

How to take, course of use and dosage

Externally, the ointment is applied to the affected areas in a thin layer 2-4 times a day; after the disappearance of painful sensations-1 time a day for 7 days.

To administer the ointment, the attached screw-on tip is used, which is inserted into the rectal cavity, and a small amount of ointment is squeezed out by lightly pressing the tube.

Description

Direct – acting anticoagulant for topical use + other medications

Description

Yellowish-white semi-transparent, gel-like ointment with a characteristic smell of lanolin.

Functional features

Heparin is 95% bound to plasma proteins after adsorption. It is released slowly from the tissues with a half-life of about 1 h. 50% of the Active ingredient remains on the skin after use. The rate of excretion depends on the dose. After absorption, it is metabolized in the liver (partially by the enzyme hepatic heparinase) and in the reticuloendothelial system. 20-50% is excreted unchanged in the urine and partly as uroheparin, which has a weak anticoagulant effect. The degree of excretion depends on the dose (lower doses have a shorter half – life in plasma). Prednisonep Rednisolone is metabolized in the liver after absorption. About 1% is excreted unchanged in the urine. Biological T 1/2 is 18-36 hours, and T 1/2 from plasma is 115-212 minutes.

Complete set

Ointment for rectal and external use. 20 g of ointment in an aluminum tube, capped with a screw cap made of plastic. The tube opening is protected by an aluminum membrane. The lid is a monolithic structure that includes a device for piercing the membrane. Tube together with the tip and instructions for use in a cardboard pack.

Special instructions

As with treatment with all other corticosteroids, caution should be exercised not to use the drug in large quantities or for a long time. The drug does not affect the ability to drive vehicles and potentially dangerous mechanisms.

Form of production

Ointment for rectal and external use

Storage conditions

Store at a temperature of 15 to 25°C. Keep out of reach of children!

Shelf

life is 3 years. Do not use after the expiration date indicated on the package.

Active ingredient

Heparin Sodium, Prednisone

Dosage form

ointment

Description

For adults, Pregnant women in the second and third trimester as prescribed by a doctor

Indications

Hemorrhoid