Hexo Broncho syrup 100mg/5ml, 150ml

Product description

Hexo Broncho® is an excellent solution for cough treatment!

Composition

5 ml of syrup contains: Active ingredient: guaifenesin-100.0 mg; excipients: levomenthol – 1,10 mg, glucose – 3492,0 mg, sucrose – 999,0 mg, ethanol 96% – 0,2595 ml, glycerol – 197,0 mg, sodium citrate – 57,0 mg, sodium saccharin and 15.0 mg sodium benzoate – 10.0 mg, citric acid monohydrate to 12.0 mg, caramel color was 6.75 mg, natural sweetener – 2,50 mg, flavor raspberry – 2.28 mg, karbomer 974 R – 0,250 mg, dye crimson [Ponceau 4R] – 0,250 mg, purified water – q. s. to 5 ml.

Clinical Pharmacology

Pharmacodynamics : Guaifenesin has a stimulating effect on the receptors of the gastric mucosa, leading to increased secretion of the glands of the gastrointestinal tract (GIT) and a reflex increase in the secretion of the glands of the respiratory tract. As a result, the viscosity decreases and the volume of bronchial secretions increases. Other effects may include stimulation of the vagus nerve endings in the bronchial glands and stimulation of certain brain centers, which in turn leads to improved sputum discharge. Guaifenesin has an expectorant effect for 24 hours. The components that make up the drug have a warming, softening and soothing effect when swallowed. Pharmacokinetics: Guaifenesin is well absorbed from the gastrointestinal tract when taken orally. In healthy adult volunteers, the maximum blood concentration (Cmax) and time to reach maximum blood concentration (TMAX) after ingestion of 600 mg of guaifenesin were approximately 1.4 mcg/ml and 15 minutes, respectively. The half-life (T 1/2) was about 1 hour, the drug was not detected in the blood after about 8 hours. Guaifenesin is metabolized in the liver. It is mainly excreted by the kidneys.

Indications

Symptomatic treatment of cough accompanied by difficult sputum discharge.

Use during pregnancy and lactation

Data on the use of the drug “Hexo Broncho” in pregnant women is not enough. Therefore, it is not recommended to use the drug during pregnancy, except in cases where the expected benefit to the mother exceeds the potential risk to the fetus. There are no data on the penetration of guaifenesin into breast milk, so breastfeeding should be discontinued for the duration of treatment.

Contraindications

• Hypersensitivity to any of the components of the drug, peptic ulcer of the stomach and duodenum 12 in the acute stage.
• Children under 12 years of age.
• Breast-feeding period.
• Sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.

Side effects

Adverse reactions identified during post-marketing use of the drug were classified as follows: very frequent (≥1/10), frequent (≥1/100, <1/10), infrequent (≥1/1000, <1/100), rare (≥1/10000, <1/1000), very rare (Disorders of the gastrointestinal tract. Very rare: abdominal pain, diarrhea, nausea, vomiting. Immune system disorders. Very rare: hypersensitivity reactions (including pruritus and urticaria), rash. Nervous system disorders. Very rare: dizziness, headache, drowsiness.

Interaction

Concomitant use with antitussive medications, including codeine-containing medications, is not recommended.

It is compatible with bronchodilators, antibacterial agents and other medications used in the treatment of bronchopulmonary diseases.

How to take, course of use and dosage

Inside. Adults and children over 12 years of age: fill a measuring cup to the 10 ml mark and take 10 ml (200 mg of guaifenesin) 4 times a day. The maximum daily dose is 40 ml (800 mg of guaifenesin).

Overdose

Symptoms of overdose are abdominal discomfort (heartburn, nausea, vomiting), drowsiness.

Treatment is symptomatic and supportive.

Description

Transparent liquid of red color with a characteristic smell, free from foreign inclusions

Special instructions

Do not take this medicine for the treatment of persistent or chronic cough, cough with bronchial asthma and cough accompanied by excessive sputum secretion, except in cases where the use of the drug is recommended by a doctor.

If after 3-5 days of taking the drug, the cough persists or along with the cough there is an increase in temperature, rash, prolonged headache, you should consult a doctor.

Information for patients with diabetes mellitus: the carbohydrate content in one dose of the drug corresponds to 0.75 bread units (XE).

The drug “Hexo Broncho” contains 96% ethanol (0.5 ml/10 ml of syrup). The ethanol content should be taken into account in patients suffering from alcoholism, women during pregnancy and lactation, children and people belonging to high-risk groups, such as patients with liver diseases, epilepsy, traumatic brain injury, and brain diseases.

The metabolite of guaifenesin can cause discoloration in the determination of 5-hydroxyindoleacetic acid and vanillylmindalic acid in the urine. The drug should be discontinued 24 hours before urine collection for this test.

If the medicine has become unusable or expired, do not pour it into the waste water and do not throw it on the street! Place the medicine in a plastic bag and put it in the trash can. These measures will help protect the environment!

Form of production

Syrup

Storage conditions

Store at a temperature not exceeding 25 °C. Keep out of reach of children.

Active ingredient

Guaifenesin

Dosage form

oral spray

Description

Children over 12 years old, For adults

Indications

Bronchitis, Cold, Cough, Respiratory Tract Infections