Composition
Active ingredient:
hexetidine 0.1 g / 100 ml (0.1%);
Auxiliary substances:
ethanol 96% (4.33 g / 100 ml solution);
polysorbate 60;
peppermint oil;
anise oil;
citric acid monohydrate;
sodium saccharin;
levomentol;
methyl salicylate;
clove oil;
eucalyptus oil;
azorubin 85% (E 122);
purified water
Pharmacological action
Geksoral – deodorizing, antiseptic, enveloping, hemostatic, antifungal, analgesic.
Pharmacodynamics
The antimicrobial effect of Hexoral is associated with the suppression of oxidative reactions of bacterial metabolism (thiamine antagonist). The drug has a wide range of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, but the drug Hexoral can also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus. At a concentration of 100 mg / ml, the drug suppresses most bacterial strains.
No stability development was observed. Hexetidine has a weak anesthetic effect on the mucous membrane.
Pharmacokinetics
Hexetidine adheres very well to the mucous membrane and is practically not absorbed.
After a single application of the Active ingredient, its traces are found on the gum mucosa for 65 hours. In dental plaques, active concentrations persist for 10-14 hours after application.
Indications
- inflammatory and infectious diseases of the mouth and throat;
- severe, accompanied by fever or purulent diseases of the mouth and throat that requires antibiotics and sulfonamides, tonsillitis (in the complex therapy);
- sore throat (including tonsillitis with the defeat of the side bolsters, angina Plaut-Vincent);
- pharyngitis;
- gingivitis and bleeding gums;
- periodontopathy (periodontitis diseases and their symptoms);
- stomatitis (inflammation of the mucous membrane of the mouth), glossitis (inflammation of tongue), aphthous ulcers (painful inflammation of the surface tissue defects) — to prevent superinfection;
- infection of the alveoli (the holes of the teeth) after tooth extraction;
- fungal infections of the mouth and throat, especially oral thrush (a yeast infection);
- before and after surgery in the oral cavity and pharynx;
- additional oral hygiene with overall disease;
- elimination of an unpleasant smell from the mouth, especially in the case of the crumbling of tumors of the oral cavity and pharynx;
- adjunct in the treatment of colds.
Use during pregnancy and lactation
Pregnant and lactating women should consult their doctor before using the drug.
Contraindications
Hypersensitivity to any of the components of the drug; children’s age (up to 3 years).
Side effects
In some cases, hypersensitivity reactions to the drug developed.
Prolonged use may cause taste problems.
Interaction
Drug interaction of the drug Hexoral® is not described.
How to take, course of use and dosage
Locally.
General dosage recommendations
Adults and children over 3 years old. Rinse the mouth and pharynx with 15 ml of undiluted solution for at least 30 seconds. Unless otherwise indicated, apply twice a day, preferably in the morning and evening.
Hexetidine adheres to the mucous membrane and thus gives a lasting effect. In this regard, the drug should be used after meals. The drug Hexoral solution for topical application is also safe with more frequent use.
The drug Hexoral solution for topical application can only be used for rinsing the mouth and pharynx. The solution should not be swallowed.
Always use an undiluted solution for rinsing.
In the treatment of diseases of the oral cavity, the drug can also be applied with a tampon.
The duration of treatment is determined by the doctor.
Do not use in children under 3 years of age.
Overdose
Hexetidine in the indicated dosage is non-toxic.
Symptoms: ingestion of large amounts of the drug leads to vomiting, so significant absorption is not expected. No cases of alcohol poisoning from overdose have been described.
Acute alcohol poisoning is very unlikely, but theoretically possible if a large dose of the drug is swallowed by a small child.
Treatment: gastric lavage is necessary within 2 hours after ingestion of an excessive dose.
Conducting symptomatic therapy, as with alcohol intoxication. In any case of overdose, the patient should immediately consult a doctor.
Special instructions
There are no special requirements.
Hexoral® topical solution can only be used to rinse the mouth and pharynx if the patient can spit out the solution after rinsing.
Hexoral® solution for topical application contains 96% ethanol (4.33 g / 100 ml of solution).
Use in pediatrics
In children, the drug can be used from an age when there is no risk of uncontrolled ingestion when using the solution.
Product form
solution for topical application
Storage conditions
In a dark place, at a temperature not exceeding 25 °C.
Shelf life
2 years
Active ingredient
Hexatidine
Dosage form
oral spray
Description
For adults, Pregnant women as prescribed by a doctor, Children over 3 years of age, Nursing mothers as prescribed by a doctor
Indications
Flu, Sore Throat, Thrush, Stomatitis, Pharyngitis, Oral Inflammation, Periodontitis, Gum inflammation
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Side effects of Hexoral solution for external use 0.1%, 200ml
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