Hydrocortisone-Pos, eye ointment 1%, 2.5g

Composition

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of 1 g of Hydrocortisone-POS 1% eye ointment contains:

Active ingredient: Hydrocortisone Acetate 10.0 mg

Auxiliary substances: petroleum jelly, liquid paraffin, lanolin.

Pharmacological action

Pharmacotherapy group – glucocorticosteroid for topical use. ATX code S01BA02

Pharmacodynamics

The drug contains hydrocortisone acetate, a glucocorticosteroid, as the Active ingredient.

When applied topically, hydrocortisone acetate suppresses inflammatory and allergic reactions that occur in the area of the outer membranes and the anterior segment of the eye.

The effect of hydrocortisone acetate, like other corticosteroids, is based on the suppression of the function of leukocytes and tissue macrophages. It restricts the migration of white blood cells, macrophages, and mast cells to the area of inflammation and suppresses the formation of interleukin-1. It helps to stabilize lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the area of inflammation. Reduces capillary permeability due to histamine release. Inhibits fibroblast activity and collagen formation. It inhibits the activity of phospholipase A2, which leads to suppression of prostaglandin and leukotriene synthesis.

Pharmacokinetics

The penetration of hydrocortisone acetate through the cornea into the moisture of the anterior chamber of the eye is possible due to lipophilic properties. The penetration of hydrocortisone acetate into the tissues depends on the condition of the cornea and increases significantly in the case of inflammation or damage to the eye mucosa.

Indications

• Allergic conjunctivitis, blepharitis, blepharoconjunctivitis;
• Acute and chronic iritis, iridocyclitis;
• Inflammatory phenomena after surgery on the eyeball;
• Suppression of neovascularization after keratitis, chemical burns.

Use during pregnancy and lactation

To date, there are no data from clinical trials regarding the use of Hydrocortisone–POS 1%,2.5% eye ointment during pregnancy, lactation, or in children. It is possible to use Hydrocortisone-POS 1%,2.5% eye ointment for the treatment of children older than 1 year, pregnant and lactating mothers as prescribed by the attending physician, if the expected therapeutic effect exceeds the risk of possible side effects. The duration of use of the drug in this category of patients is no more than 7-10 days.

Contraindications

• Hypersensitivity to any component of the drug;
• Corneal superficial herpes and other viral eye diseases;
• Violations of the integrity of the epithelium and corneal damage;
• Tuberculosis, bacterial or fungal infections of the eyes;
• Trachoma.
• The vaccination period.

Side effects

If you have developed a side effect that is not specified in these instructions, or you are not sure about the effectiveness of the drug during treatment with Hydrocortisone–POS eye ointment 1%,2.5%, please inform your doctor or pharmacist. In very rare cases, allergic reactions are possible, such as burning, injection of sclera, contact dermatitis, dermatoconjunctivitis, eczema of the eyelids.

Long-term use of the drug can cause secondary glaucoma and complicated cataracts, so when using the drug for more than 2 weeks, as well as in patients with a history of glaucoma, it is recommended to regularly monitor intraocular pressure.

In case of side effects, you should stop using the drug and contact your doctor (ophthalmologist) as soon as possible.

Interaction

Concomitant use of Hydrocortisone-POS eye ointment 1%,2.5% and other agents that may cause an increase in intraocular pressure (for example, atropine and other cholinergic drugs) may contribute to an additional increase in intraocular pressure, especially in predisposed patients.

How to take, course of use and dosage

In the absence of other recommendations from your doctor, follow exactly these instructions for use of Hydrocortisone-POS eye ointment 1%,2.5%.

A strip of ointment 1 cm long is laid 2-3 times a day for the lower eyelid. To do this, open the tube, slightly tilt your head back and place a 1 cm long strip of ointment behind your lower shoulder. Carefully close your eyes.

Close the tube tightly after use. During the application of eye ointment, avoid contact of the tube with the surface of the skin or conjunctiva.

With the simultaneous use of several eye medications, it is recommended to lay Hydrocortisone-POS eye ointment 1%,2.5% no earlier than 15 minutes after using eye drops.

The duration of treatment with Hydrocortisone-POS eye ointment 1%,2.5% usually does not exceed 2, maximum 3 weeks.

Overdose

When applied topically at the recommended dose, no symptoms of overdose were observed.

Description

White with a yellowish tinge homogeneous suspension ointment.

Special instructions

During treatment with Hydrocortisone–POS eye ointment 1%,2.5%, it is not recommended to use contact lenses. Immediately after the use of Hydrocortisone-POS eye ointment 1%,2.5%, a short-term visual acuity disorder may occur, leading to a slowdown in mental and physical reactions. Therefore, it is not recommended to use the drug immediately before working with mechanisms and driving vehicles.

Form of production

Eye ointment 1%,2.5%.2.5 g each in aluminum tubes, with a polyethylene tip and a screw-on lid. The tube together with the instructions for use is placed in a cardboard box.

Storage conditions

Store at a temperature not exceeding 25 ° C. Keep out of reach of children!

Expiration date

In unopened original packaging: 3 years. Do not use after the expiration date indicated on the package.

Active ingredient

Hydrocortisone

Dosage form

ointment