ATC code | J01DH01 |
---|---|
CAS Number | 68938-86-2 |
Other product names | Imipenem and Cilastatin for Injection; Imipenem and Cilastatin for Injection, USP; Primaxin; RAN-Imipenem-Cilastatin |
Dosage form | Powder for preparation of solution for infusions |
Active ingredient | Imipenem and Cilastatin |
Other ingredients | Sodium chloride |
Pharmacological classification | Antibiotic |
Pharmacological action | Imipenem exerts a bactericidal action by inhibiting cell wall synthesis in aerobic and anaerobic gram-positive and gram-negative bacteria |
Storage conditions | Store at room temperature |
Imipenem and Cilastatin Jodas Powder: A Powerful Antibiotic
Treating major bacterial infections in adults and children, imipenem with cilastatin Jodas powder is a strong antibiotic. Two drugs make up this combo: cilastatin, a renal dehydropeptidase inhibitor, and imipenem, a carbapenem antibiotic. Imipenem kills bacteria by inhibiting their formation of cell walls. Through kidney protection from breakdown, cilastatin helps imipenem remain active in the body. Against a range of germs, including those resistant to other antibiotics, this pair makes imipenem and cilastatin Jodas a powerful weapon.
Composition of Imipenem and Cilastatin Jodas Powder
Combining imipenem, cilastatin sodium, and sodium bicarbonate, imipenem and Cilastatin Jodas powder is a sterile mixture. Since it is meant to be reconstituted into a solution for intravenous infusion—that is, given straight into a vein—it facilitates quick action against the illness and fast absorption into the bloodstream.
Benefits and Results of Imipenem and Cilastatin Jodas Powder
Broad-spectrum antibiotics like imipenem and cilastatin Jodas are effective against both gram-positive and gram-negative bacteria since they Its frequently used to treat tough to control major infections for which other antibiotics are insufficient. Several of the main advantages of this drug include:
- Strong against a range of microorganisms, including those resistant to other antibiotics.
- Quick absorption into the bloodstream, producing a quick response against the infection
- Treats major infections affecting several organs by means of this approach
What is Imipenem and Cilastatin Jodas Powder Used For?
Serious bacterial infections, especially those resistant to conventional antibiotics, are appropriate for treatment with imipenem and cilastatin Jodas powder. Its used frequently to treat infections affecting:
- Reduced respiratory tract (pneumonia)
- Skin and architectural features
- The urinary tract
- Abdomen
- Obstacles in Gynecological Organs
- Blood (sepsis)
- Bones and joints
- Meninges—menningitis—
- Endocarditis, the heart
How is Imipenem and Cilastatin Jodas Powder Administered?
A healthcare provider gives imipenem and cilastatin Jodas powder intravenously (IV). Usually, it is infused slowly over twenty to sixty minutes. Other factors include the degree of the infection, the patients age, and others that will affect the dosage and frequency of administration.
Dosage and Administration of Imipenem and Cilastatin Jodas Powder
A healthcare provider decides the Imipenem and Cilastatin Jodas powder dosage depending on the particular patients demand. Usually given as a gradual intravenous infusion over 20 to 60 minutes, The degree of the infection, the patients age, and other factors may all affect the dosage and frequency of administration. You should pay great attention to the directions your doctor or other healthcare provider offers.
Side Effects of Imipenem and Cilastatin Jodas Powder
Though not everyone experiences them, Imipenem and Cilastatin Jodas might have adverse effects, just as all drugs. Several typical side effects consist in:
- Sickness
- Retching
- Rash, diarrhea
- Itching
- Headache
Rarely, more major side effects could develop. Should you have any odd or severe side effects, you should get in touch with your doctor right away.
Contraindications of Imipenem and Cilastatin Jodas Powder
Not everyone would benefit from Imipenem with Cilastatin Jodas powder. If you have any allergies or medical conditions—especially if you are allergic to penicillin or other antibiotics—have a history of seizures—have kidney or liver problems—then you should tell your doctor.
Pregnant or nursing?
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