Impaza, pills for dissolution, 20pcs

Composition

Active ingredients: Affinity-purified antibodies to endothelial NO synthase – 0.003 g*. Excipients: lactose monohydrate 0.267 g, microcrystalline cellulose 0.03 g, magnesium stearate 0.003 g. * applied to lactose monohydrate in the form of a water-alcohol mixture containing no more than 10 -15 ng / g of the active form of the Active ingredient.

Pharmacological action

Increases the activity of endothelial NO-synthase, restores the production of nitric oxide (NO) by the endothelium during sexual stimulation, increases the content of cyclic guanosine-2 monophosphate (cGMP) in smooth muscles and promotes their relaxation, which leads to an increase in blood filling of the cavernous bodies and provides an erection of sufficient strength and duration. The drug increases libido (sexual desire) and satisfaction with sexual intercourse. Regular use of the drug increases the level of testosterone in the serum (with a moderately reduced baseline).

Pharmacokinetics

The sensitivity of modern physico-chemical methods of analysis(gas-liquid chromatography, high-performance liquid chromatography, chromato-mass spectrometry) does not allow us to assess the content of the Active ingredient of Impaza in biological fluids, organs and tissues due to the specific composition of the drug (see the section “Composition (per 1 tablet)”), which makes it technically impossible to study pharmacokinetics.

Indications

Impaza is indicated for use in adults. Erectile dysfunction (erectile dysfunction) of various origins.

Use during pregnancy and lactation

Impaza is not intended for use in women.

Contraindications

Increased individual sensitivity to the components of the drug; age up to 18 years; lactase deficiency, lactose intolerance, glucose-galactose malabsorption.

Side effects

Possible reactions of increased individual sensitivity to the components of the drug.

Interaction

It is possible to use Impaza against the background of taking nitrates in patients with ischemic heart disease (angina pectoris of functional class I-II), as well as use in conjunction with beta-blockers, diuretics, angiotensin-converting enzyme (ACE) inhibitors, calcium antagonists.

How to take, course of use and dosage

It is not intended to divide the tablet into parts. At one time – 1 tablet (keep in the mouth until fully dissolved-not during meals). To improve the erection (ability to have sexual intercourse), a therapeutic and preventive course lasting at least 12 weeks is recommended for 1 tablet 1-2 times a day. If necessary, the course therapy can be repeated in 3-6 months.

Overdose

In case of accidental overdose, dyspeptic phenomena are possible due to the fillers included in the dosage form.

Description

Tablets are flat-cylindrical in shape with a risk and chamfer, from white to almost white in color. On the flat side with a risk, the inscription MATERIA MEDICA is applied, on the other flat side, the inscription IMPAZA is applied.

Special instructions

The drug contains lactose monohydrate, and therefore it is not recommended to prescribe it to patients with congenital galactosemia, glucose or galactose malabsorption syndrome, or with congenital lactase deficiency.

Storage conditions

In a place protected from light, at a temperature not exceeding 25°C. Keep out of reach of children.

Shelf

life is 3 years. Do not use after the expiration date.

Active ingredient

Antibodies

Dosage form

resorption tablets