Jocet, bottle, 100ml

Composition

of 5 ml:

– salbutamol sulfate 1.255 mg, which corresponds to the content of salbutamol 1 mg

-Bromhexinee hydrochloride 2 mg

-guaifenesin 50 mg

-menthol (levomentol) 500 mcg

Auxiliary substances:

sodium methylparahydroxybenzoate,

sodium propylparahydroxybenzoate,

sucrose,

propylene glycol,

sodium saccharinate,

sorbic acid,

glycerol,

citric acid monohydrate,

sorbitol (non-crystallizing) liquid,

sunset yellow dye,

purified water.

Pharmacological action

Jocet is a combined drug that has a bronchodilator, expectorant, mucolytic effect. – Salbutamol is a bronchodilator that stimulates the beta2-adrenergic receptors of the bronchi, prevents or stops bronchospasm. – Bromhexinee-mucolytic agent, has an expectorant and weak antitussive effect. Reduces the viscosity of sputum due to depolarization of acidic mucopolysaccharides and stimulation of secretory cells of the bronchial mucosa. Activates the cilia of the ciliated epithelium, improving sputum discharge. Guaifenesin-reduces the surface tension and adhesive properties of sputum, increases the serous component of bronchial secretions, reduces the viscosity of sputum, activates the ciliary apparatus of the bronchi, facilitates sputum removal and promotes the transition of an unproductive cough to a productive one. – Menthol-has an antispasmodic effect, gently stimulates the secretion of bronchial glands, has antiseptic properties, has a calming effect and reduces irritation of the mucous membrane of the respiratory tract.

Indications

Acute and chronic bronchopulmonary diseases accompanied by difficulty in sputum discharge: — bronchial asthma; – chronic bronchitis— – emphysema of the lungs— – COPD; – tracheobronchitis;— pneumonia— – pneumoconiosis;- tuberculosis of the lungs.

Contraindications

-tachyarrhythmia— – myocarditis;— aortic stenosis— – decompensated diabetes mellitus;- thyrotoxicosis;— glaucoma— – hepatic and / or renal failure;— peptic ulcer of the stomach and duodenum in the acute phase; – gastric bleeding— – pregnancy; – lactation (breastfeeding);- hypersensitivity to the components of the drug Jocet. With caution, the drug should be used with diabetes mellitus, arterial hypertension, peptic ulcer of the stomach and duodenum in the anamnesis; simultaneously with antitussives, non-selective beta-blockers, MAO inhibitors.

Side effects

From the central nervous system: headache, dizziness, increased nervous excitability, sleep disturbance, drowsiness, tremor, convulsions.

From the digestive system: nausea, vomiting, diarrhea, exacerbation of peptic ulcer of the stomach and duodenum; very rarely-increased activity of hepatic transaminases.

From the cardiovascular system: tachycardia, decreased blood pressure, collapse.

From the urinary system: staining of urine in pink color.

Allergic reactions: skin rash, urticaria, paradoxical bronchospasm.

Interaction

Beta-2-adernomimetic agents, theophylline and other xanthines when used simultaneously with the drug increase the likelihood of developing tachyarrhythmias.

MAO inhibitors and tricyclic antidepressants enhance the effect of salbutamol, can lead to a sharp decrease in blood pressure. Diuretics and corticosteroids enhance the hypokalemic effect of salbutamol.

Concomitant use with drugs containing codeine and other antitussive agents makes it difficult to remove diluted sputum.

Bromhexinee, which is part of the drug, promotes the penetration of antibiotics into the lung tissue.

It is not recommended to use simultaneously with non-selective beta – blockers.

How to take, course of use and dosage

The drug should be taken orally.

Children under 6 years of age – 1 tsp (5 ml) 3 times/day; from 6 to 12 years-1-2 tsp (5-10 ml) 3 times/day.

Adults and children over 12 years of age – 2 tsp (10 ml) 3 times / day.

Overdose

Symptoms: increased manifestations of side effects. Treatment: symptomatic therapy.

Special instructions

Guaifenesin turns the urine pink.

It is not recommended to drink the drug with an alkaline drink.

Form of production

Syrup.

Storage conditions

At a temperature not exceeding 30 °C

Shelf life

2 years

Active ingredient

Broigexin, Guaifenizine, Salbutamol, Menthol (Levomentol)

Conditions of release from pharmacies

By prescription

Dosage form

solution for oral use

Description

For adults as prescribed by a doctor, for children as prescribed by a doctor

Indications

Pneumonia, Bronchospasm, Cough, Bronchial asthma, Chronic Obstructive Pulmonary Disease, Bronchitis, Tuberculosis