Ketoprofen-Lor gargle solution 16mg/ml vial, 200ml

Composition

Active ingredient: ketoprofen lysine salt — 16.0 mg. Auxiliary substances: glycerol — 200,0 mg, ethanol (ethyl alcohol 95%) in terms of absolute alcohol to 40.0 mg (37,0 mg), methyl parahydroxybenzoate (nipagin) – 1,5 mg, levomenthol (L-menthol) – 0,70 mg, sodium saccharin –Nd 2.0 mg, sodium hydrogen phosphate, dodecahydrate – 0,78 mg, flavor mint of 2.40 mg of brilliant green – 0.016 mg, purified water – up to 1 ml.

Pharmacological action

It has an anti-inflammatory, analgesic effect. By inhibiting cyclooxygenase type I and II, it inhibits the synthesis of inflammatory mediators (prostaglandins, thromboxane, etc. ). It stabilizes lysosomal membranes and delays the release of enzymes that promote tissue destruction during inflammation. Inhibits neutrophil activity. It has anti-radikinin activity. The drug does not have an antibacterial effect. Pharmacokinetics A single dose of 160 mg leads to a plasma level of less than 400 ng / ml, insufficient for systemic action.

Indications

Symptomatic treatment of inflammatory diseases of the upper respiratory tract – tonsillitis (sore throat), laryngitis, pharyngitis; inflammatory diseases of the oral cavity stomatitis, gingivitis, glossitis, aphthus, periodontal disease, chronic periodontal disease; as an analgesic agent for dental manipulations. If necessary, please consult your doctor before using the medicine.

Use during pregnancy and lactation

The use of the drug in the third trimester of pregnancy is contraindicated. The use of the drug in the first and second trimesters of pregnancy is possible only after consultation with a doctor, if the intended benefit to the mother exceeds the potential risk to the fetus. The use of the drug during breastfeeding is not recommended.

Contraindications

Hypersensitivity to ketoprofen and other components of the drug, acetylsalicylic acid or other NSAIDs, complete or incomplete combination of bronchial asthma, recurrent polyposis or paranasal sinuses and intolerance to acetylsalicylic acid and other NSAIDs (including in the anamnesis), children under 12 years of age.

With caution

Erosive and ulcerative lesions of the gastrointestinal tract (exacerbation), Crohn’s disease, diverticulitis, peptic ulcer, hemophilia, etc. blood clotting disorders, chronic heart failure, bronchial asthma, old age, pregnancy (I and II trimester).

Side effects

Allergic reactions. If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

How to take, course of use and dosage

For mouthwash. 10 ml of the drug (dose for 1 application) should be measured using a measuring cup included in the package, and diluted in 100 ml (half a glass) of drinking water. Mouthwash is performed 2 times a day, preferably in the morning and evening. The drug should be used after meals. The duration of treatment is determined by the doctor. If there is no improvement after treatment or new symptoms appear, you should consult your doctor. Use the drug only according to the method of application and in the doses indicated in the instructions for use. If necessary, please consult your doctor before using the medicine.

Overdose

When using the drug in accordance with the instructions for use, overdose is unlikely. Accidental ingestion of the solution does not lead to serious consequences, because a single dose for rinsing contains 160 mg of ketoprofen lysine salt, which corresponds to the dose intended for oral use.

Special instructions

Prolonged use may cause hypersensitivity reactions.

In this case, you should stop using the drug and choose adequate treatment methods.

With high doses and a long course of treatment, absorbed ketoprofen can compete with other drugs that have a high affinity for plasma proteins.

The drug contains methyl parahydroxybenzoate, which can cause allergic reactions (including delayed-type allergic reactions).

Please read the instructions carefully before you start using the drug. Save the instructions, you may need them again. If you have any questions, contact your doctor. The medicine you are being treated with is intended for you personally, and it should not be passed on to others, as it can cause harm to them even if you have the same symptoms as you do.

Influence on the ability to drive vehicles and mechanisms

The drug does not affect the ability to drive vehicles or engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Storage conditions

Store at a temperature not exceeding 25 °C. Keep out of reach of children.

Shelf

life is 2 years. Do not use after the expiration date indicated on the package.

Active ingredient

Ketoprofen

Dosage form

topical solution