Klindatsin, vaginal suppositories 100mg, 3pcs

Composition

Clindamycin

Auxiliary substances:

semisynthetic glycerides

Pharmacological action

CLINDACIN is an antibiotic from the lincosamide group, has a wide spectrum of antimicrobial action. The mechanism of action is due to binding to the 50S subunit of the ribosomal membrane and suppression of protein synthesis in the microbial cell. It acts bacteriostatically. In relation to a number of gram-positive cocci, a bactericidal effect is possible.

Active against Staphylococcus spp. (including Staphylococcus epidermidis, and reproducirse producing penicillinase), Streptococcus spp. (except Enterococcus faecalis), Streptococcus pneumoniae, Corynebacterium diphtheriae, Mycoplasma spp., anaerobic and microaerophilic gram-positive cocci (including Peptococcus spp. and Peptostreptococcus spp. ), Clostridium perfringens, Clostridium tetani, Bacteroides spp. (including Bacteroides fragilis and Prevotella melaninogenica), Fusobacterium spp., Propionibacterium spp. Eubacterium spp. and Actinomyces israelii.

Most strains of Clostridium perfringens are sensitive to clindamycin, but other species of Clostridium spp. (including Clostridium sporogenes, Clostridium tertium) are resistant to its action, and therefore, for infections caused by Clostridium spp., it is recommended to determine the antibioticogram.

There is cross-resistance between clindamycin and lincomycin.

Indications

Bacterial vaginosis caused by drug-sensitive microorganisms.

Contraindications

-I trimester of pregnancy—

– hypersensitivity to the components of the drug.

Interaction

Clindacin ® enhances the action of rifampicin, aminoglycosides – streptomycin, gentamicin.

Increases muscle relaxation caused by n-holinoblokatorami.

Clindacin® is incompatible with erythromycin, ampicillin, diphenylhydantoin derivatives, barbiturates, aminophylline, calcium gluconate and magnesium sulfate.

How to take, course of use and dosage

Assign intravaginally 1 suppository 1 time/day. just before bedtime, for 3-7 consecutive days.

Before use, one suppository is released from the contour package, after cutting the film along the contour of the suppository, it is inserted, if possible, deep into the vagina, in the supine position.

Form of production

Vaginal suppositories

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 20 °C

Shelf life

3 years

Active ingredient

Clindamycin

Dosage form

vaginal suppositories

Description

For adults, Women, and Children over 12 years of age

Indications

Bacterial Vaginosis, Vaginosis, Vaginal Candidiasis