Klindovit, gel 1%, 30g

Composition

1 g of gel for external use contains:  

Clindamycin (in the form of phosphate) 10 mg.

Auxiliary substances:  

Methyl parahydroxybenzoate (nipagin),

allantoin,

tocopherol phosphate, disodium lauryliminodipropionate,

propylene glycol,

macrogol 400 (polyethylene oxide 400),

carbomer (copolymer, interpolymer),

sodium hydroxide,

purified water.

Pharmacological action

This antibiotic from the lincosamide group affects all strains Propionibacterium acnes. After application to the skin surface, the product quickly penetrates the upper layers, accumulates in comedones, showing significant antibacterial activity.

At the same time, the average concentration of an antibiotic in the composition of comedones exceeds the minimum indicator of suppressing strains. Propionibacterium acnes, which are the causative agents of acne. From the moment the gel is applied to the skin, a fairly low concentration of clindamycin is detected in the blood plasma and urine.

Indications

Acne.

Use during pregnancy and lactation

Clindovit can be used externally during pregnancy if the intended benefit of therapy for the mother exceeds the potential risk to the fetus.

If it is necessary to use during lactation, it is recommended to stop breastfeeding.

Contraindications

-Crohn’s disease. – Pseudomembranous colitis (including in the anamnesis). – Ulcerative colitis (including in the anamnesis). – Hypersensitivity to clindamycin or lincomycin.

With caution:

– In patients under 12 years of age (safety and efficacy data are not available).

– During lactation (breastfeeding).

– In patients predisposed to the development of allergic reactions.

– When taking muscle relaxants at the same time.

Side effects

The drug is usually well tolerated.

– Local reactions: Possible irritation (at the site of application), burning, itching, dry skin, erythema, peeling, increased sebum production, contact dermatitis.

– Systemic reactions: Pseudomembranous enterocolitis (the probability of development is present with systemic absorption of clindamycin).

Interaction

Clindamycin and erythromycin are antagonists, so simultaneous use of these antibiotics is not recommended. There is cross-resistance between clindamycin and lincomycin.

Clindamycin may increase the effect of muscle relaxants, disrupting neuromuscular transmission.

How to take, course of use and dosage

The drug is used externally.

The gel is applied in a thin layer on the affected part of the previously cleaned and dried skin 2-3 times a day. To achieve a therapeutic effect, treatment should be continued for 6-8 weeks, and if necessary, it can be continued for up to 6 months.

Special instructions

When applying the product, avoid contact with the eyes and mouth, and after applying the gel, wash your hands.

Form of production

Gel.

Storage conditions

At a temperature of 15-25 °C.

Shelf

life is 2 years.

Active ingredient

Clindamycin

Dosage form

gel for external use

Description

Children over 12 years old, For adults

Indications

Acne